Research Article

Platelet Consumption and Filter Clotting Using Two Different Membrane Sizes during Continuous Venovenous Haemodiafiltration in the Intensive Care Unit

Table 1

Baseline patient characteristics and laboratory parameters at CVVHDF start.

All patients
( )
Filter AV 1000S
( )
Filter AV 600S
( )
value

Age—yr68 (35–87)68 (35–87)67 (35–86)0.82
Male sex—number (%)21 (64%)11 (65%)10 (63%)0.90
BMI—kg/m224.6 (14.6–41.5)26.7 (18.3–41.5)20.8 (14.6–37.7)0.07
SOFA score12 (8–16)12 (8–15)12 (8–16)0.58
SAPS II score63 (30–98)63 (30–98)60 (37–94)0.87
Noradrenaline—number (%)23 (69.7%)13 (76.5%)10 (62.5%)0.38
Mechanical ventilation—number (%)24 (72.7%)13 (76.5%)11 (68.7%)0.56
Admission diagnoses—number (%)0.33
 Cardiovascular10 (30.3%)7 (41.2%)3 (18.8%)
 Sepsis9 (27.3%)5 (29.4%)4 (25.0%)
 Respiratory4 (12.1%)1 (5.9%)3 (18.8%)
 Others10 (30.3%)4 (23.5%)6 (37.4%)
Length of ICU stay—days8 (1–168)8 (3–44)8 (1–168)0.79
Length of hospital stay—days22 (2–171)19.5 (3–61)25.5 (2–171)0.53
ICU mortality— . (%)11 (33.3%)7 (41.2%)4 (25.0%)0.33
Hospital mortality— (%)14 (42.4%)8 (47.1%)6 (37.5%)0.58
Creatinine—umol/L299 (26–909)320 (210–649)262 (26–909)0.28
BUN—mmol/L21.9 (2.8–40.1)20.1 (2.8–40.1)22.1 (3.8–37.3)0.68
Potassium—mmol/L4.8 (3.2–6.7)5.3 (3.9–6.7)4.6 (3.2–6.4)0.03
pH7.30 (6.86–7.49)7.30 (7.04–7.44)7.28 (6.86–7.49)0.64
Lactate—mmol/L1.2 (0.5–14.7)1.5 (0.5–4.3)1.1 (0.5–14.7)0.46
Bicarbonate—mmol/L17.9 (6.1–29.8)19.5 (11.1–29.8)16.3 (6.1–29.3)0.18
Platelet count—1/uL 189,000 (47,000–522,000)189,000 (95,000–522,000)191,500 (47,000–422,000)0.59
Haemoglobin—g/dL8.9 (6.7–15.3)9.1 (7.7–10.2)8.9 (6.7–15.3)0.82
Renal function before admission to ICU 0.42
 GFR > 60 mL/min15 (45.5%)9 (52.9%)6 (37.5%)
 GFR < 60 mL/min17 (51.5%)8 (47.1%)9 (56.3%)

Results are given as median (range) or percentages; BMI: body mass index; SOFA: sequential organ failure assessment; BUN: blood urea nitrogen; GFR: glomerular filtration rate.
Total number of patients = 32; filter AV 1000S = 17; filter AV 600S = 15.