Research Article
Delirium during Weaning from Mechanical Ventilation
Table 1
Characteristics of the patients included in the study.
| | Variables | Total
() | Delirium
()
(53.1%) | No delirium
()
(46.9%) | |
| | Age (years), mean ± SD | | | | Ns | | SOFA score (admission), mean ± SD | | | | Ns | | APACHE II score (admission), mean ± SD | | | | Ns | | Male, (%) | 44 (68.8%) | 25 (73.5%) | 19 (63.3%) | Ns | | Sedation (days), mean ± SD | | | | Ns | | Midazolam, total cumulative dose (mg), mean ± SD | | | | Ns | | Length of MV until 1st assessment (days), mean ± SD | | | | Ns | | Time between sedation withdrawal and 1st assessment (h), mean ± SD | | | | Ns | | Length of stay in ICU until 1st assessment (days), mean ± SD | | | | Ns | | Cause of hospital admission, (%) | | | | | | Neurological (including trauma) | 24 (37.5%) | 18 (52.9%) | 6 (20.0%) | 0.014 | | TBI | 16 (25%) | 13 (38.3%) | 3 (10%) | | | SCI | 1 (1.6%) | 0 | 1 (3.4%) | | | Meningitis | 2 (3.1%) | 2 (5.9%) | — | | | Stroke | 2 (3.1%) | 1 (2.9%) | 1 (3.3%) | | | Convulsive status | 2 (3.1%) | 1 (2.9%) | 1 (3.3%) | | | Cerebral tumour | 1 (1.6%) | 1 (2.9%) | — | | | Medical | 21 (52.7%) | 9 (26.5%) | 12 (40%) | Ns | | ARF | 14 (21.9%) | 5 (14.7%) | 9 (30.0%) | | | Exacerbated COPD | 6 (9.4%) | 4 (11.8%) | 2 (6.7%) | | | Others | 1 (1.6%) | — | 1 (3.3%) | | | Surgical/nonneurological trauma | 19 (29.7%) | 7 (20.6%) | 12 (40%) | ns | | Firearm injury | 7 (10.9%) | 4 (11.8%) | 3 (10%) | | | Penetrating stab injury | 1 (1.6%) | 1 (3.0%) | — | | | Thoracoabdominal trauma | 4 (6.3%) | 1 (2.9%) | 3 (10%) | | | Postoperative | 7 (10.9%) | 1 (2.9%) | 6 (20%) | |
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Ns: not significant; SD: standard deviation; SOFA: sequential organ failure assessment; APACHE: acute physiology and chronic health evaluation; MV: mechanical ventilation; ICU: intensive care unit, TBI: traumatic brain injury; SCI: spinal cord injury; ARF: acute respiratory failure; COPD: chronic obstructive pulmonary disease.
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