Dose-Dependent Hemodynamic, Biochemical, and Tissue Oxygen Effects of OC99 following Severe Oxygen Debt Produced by Hemorrhagic Shock in Dogs

<div>(a) OC99 plasma hemoglobin (Hb<sub>p</sub>) concentration versus tissue oxygen tension (tPO<sub>2</sub>). (b) OC99 Hb<sub>p</sub> concentration versus mean pulmonary artery (PAP) pressure. (c) Change in PAP when 0.65 g/kg OC99 is administered at 30 ml/kg/hr or 10 ml/kg/hr; each symbol represents a different dog. Solid circles: Hextend without OC99; open circles: repeat doses of Hextend with increasing concentrations of OC99 administered over 10 minutes. Solid triangle: Hextend with OC99 administered over 30 minutes.</div>

Critical Care Research and Practice

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Figure 1

Figure 1: Dose-Dependent Hemodynamic, Biochemical, and Tissue Oxygen Effects of OC99 following Severe Oxygen Debt Produced by Hemorrhagic Shock in Dogs 

Figure 1 | Dose-Dependent Hemodynamic, Biochemical, and Tissue Oxygen Effects of OC99 following Severe Oxygen Debt Produced by Hemorrhagic Shock in Dogs 