Research Article

Does Obesity Predispose Medical Intensive Care Unit Patients to Venous Thromboembolism despite Prophylaxis? A Retrospective Chart Review

Table 1

Baseline demographics.

BMI < 30 kg/m2BMI ≥ 30 kg/m2

Male (%)159 (56%)126 (46%)0.016
Average BMI (SD), kg/m224.8 (3.3)38.8 (8.8)
Age (SD)61.8 (16.9)64.2 (14.2)0.074
Primary reason for admission0.014
 Cardiovascular22 (7.7%)14 (5.1%)
 Respiratory151 (53%)133 (48%)
 Gastrointestinal10 (3.5%)19 (6.9%)
 Renal7 (2.5%)11 (4%)
 Neurologic19 (6.7%)8 (2.9%)
 Sepsis50 (17.5%)74 (26.8%)
 Metabolic6 (2.1%)5 (2%)
 Other20 (7%)12 (4.3%)
Active hematologic or oncologic process50 (17.5%)35 (12.7%)0.108
Documented sleep apnea20 (7%)85 (30.8%)<0.001
History of thrombosis15 (5.3%)20 (7.2%)0.332
 Treatment of thrombosis15 (100%)19 (95%)
 complete
Antiplatelet agents0.0021
 Aspirin89 (31.2%)119 (43%)
 Clopidogrel1 (0.5%)4 (1.5%)
 Both9 (3.2%)14 (5.1%)
1-hour acute physiology score (SD)36 (19.5)38.5 (20.1)0.14
24-hour acute physiology score (SD)62.8 (21.4)66 (21.5)0.075
Dialysis0.203
 Chronic15 (5.3%)18 (6.5%)
 New/acute26 (9.1%)37 (13.4%)
Mechanical ventilation0.119
 Noninvasive45 (15.8%)65 (23.6%)
 Invasive112 (39.3%)92 (33.3%)
 Both72 (25.3%)65 (23.6%)
IVC filter11 (3.9%)7 (2.5%)0.374
Mechanical VTE prophylaxis device119 (41.7%)88 (31.3%)0.015
Subcutaneous heparin282 (98.9%)270 (97.8%)
Subcutaneous dalteparin3 (1.1%)6 (2.2%)