Antimicrobial Doses in Continuous Renal Replacement Therapy: A Comparison of Dosing Strategies

Table 1

Equations proposed for determining appropriate medication dose for a patient undergoing continuous renal replacement therapy (CRRT).

Author	Equation
Bugge [4]	Normal:
	AKI:
	CKD5:
Kroh [5]	Normal:
	AKI:
	CKD5:
Reetze-Bonorden [6]	AKI:
	CKD5:

, dose in CRRT.
, dose in normal renal function.
, dose in anuric patient.
, nonrenal clearance in normal healthy patient.
, nonrenal clearance in anuric patient with AKI.
, nonrenal clearance in anuric patient with .
, total body clearance in normal healthy patient.
, ultrafiltration rate.
, sieving coefficient.