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Critical Care Research and Practice
Volume 2017, Article ID 8046240, 8 pages
Research Article

Factors Associated with the Incidence and Severity of New-Onset Atrial Fibrillation in Adult Critically Ill Patients

1Hospital do Câncer (UOPECCAN) and Hospital Universitário and Hospital São Lucas, Cascavel, PR, Brazil
2Hospital São Lucas, Cascavel, PR, Brazil
3Curso de Medicina, Faculdade Assis Gurgacz, Cascavel, PR, Brazil
4Hospital Universitário, Cascavel, PR, Brazil
5Hospital Bom Jesus, Toledo, PR, Brazil
6Hospital Nossa Senhora Salete, Cascavel, PR, Brazil
7Hospital Costa Cavalcanti, Foz do Iguaçu, PR, Brazil

Correspondence should be addressed to Péricles A. D. Duarte; rb.etseoinu@etraud.selcirep

Received 2 February 2017; Revised 7 April 2017; Accepted 30 April 2017; Published 15 June 2017

Academic Editor: Robert Boots

Copyright © 2017 Péricles A. D. Duarte et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Acute Atrial Fibrillation (AF) is common in critically ill patients, with significant morbidity and mortality; however, its incidence and severity in Intensive Care Units (ICUs) from low-income countries are poorly studied. Additionally, impact of vasoactive drugs on its incidence and severity is still not understood. This study aimed to assess epidemiology and risk factors for acute new-onset AF in critically ill adult patients and the role of vasoactive drugs. Method. Cohort performed in seven general ICUs (including cardiac surgery) in three cities in Paraná State (southern Brazil) for 45 days. Patients were followed until hospital discharge. Results. Among 430 patients evaluated, the incidence of acute new-onset AF was 11.2%. Patients with AF had higher ICU and hospital mortality. Vasoactive drugs use (norepinephrine and dobutamine) was correlated with higher incidence of AF and higher mortality in patients with AF; vasopressin (though used in few patients) had no effect on development of AF. Conclusions. In general ICU patients, incidence of new-onset AF was 11.2% with a high impact on morbidity and mortality, particularly associated with the presence of Acute Renal Failure. The use of vasoactive drugs (norepinephrine and dobutamine) could lead to a higher incidence of new-onset AF-associated morbidity and mortality.