| | | Nonsurvivors
(53.8%) | Survivors
(46.2%) | Total
| p value |
| | Diagnosis | | | | | | Isolated pulmonary TB, (%) | 18 (64.3) | 10 (35.7) | 28 (71.8) | 0.037 | | Pulmonary and extrapulmonary TB, n (%) | 2 (25.0) | 6 (75.0) | 8 (20.5) | 0.112 | | Isolated extrapulmonary TB, n (%) | 1 (33.3) | 2 (66.7) | 3 (7.7) | 0.586 | | Pulmonary TB () | | | | | | Microbiological data | | | | | | Positive smear for AFB, (%) | 17 (68.0) | 8 (32.0) | 25 (69.4) | 0.034 | | Positive cultural examination, (%) | 19 (63.3) | 11 (36.7) | 30 (83.3) | 0.069 | | Positive PCR (), (%) | 14 (73.7) | 5 (26.3) | 19 (61.3) | 0.008 | | Radiological findings | | | | | | Miliary radiological pattern, (%) | 8 (61.5) | 5 (38.4) | 13 (36.1) | 0.587 | | Cavitary disease, (%) | 4 (6.7) | 2 (33.3) | 6 (16.7) | 0.672 | | Multilobar involvement (≥3), (%) | 16 (57.1) | 12 (42.9) | 28 (77.8) | 1 | | ICU admission | | | | | | Physiological score | | | | | | APACHE II, median (IQR) | 30.0 (12.75) | 20.5 (17.00) | 26.0 (15.75) | 0.030 | | SAPS II, medina (IQR) | 58.0 (23.5) | 42.5 (38.50) | 55.0 (27.5) | 0.014 | | Early ICU admission, (%) | 8 (40.0) | 12 (60.0) | 20 (51.3) | 0.075 | | Reasons for ICU admission | | | | | | Respiratory failure, (%) | 10 (50.0) | 10 (50.0) | 20 (51.3) | 0.621 | | Severe sepsis/septic shock, (%) | 7 (87.5) | 1 (12.5) | 8 (20.5) | 0.049 | | Decreased consciousness, (%) | 0 | 2 (100) | 2 (5.1) | 0.206 | | Post-CPR, (%) | 3 (75.0) | 1 (25.0) | 4 (10.3) | 0.609 | | Post-surgical procedure, (%) | 1 (20.0) | 4 (80.0) | 5 (12.8) | 0.162 | | Physiological support | | | | | | Mechanical ventilation, (%) | 17 (65.4) | 9 (34.6) | 26 (66.7) | 0.041 | | Vasopressor infusion, (%) | 11 (78.6) | 3 (21.4) | 14 (35.9) | 0.02 | | Acute renal failure, (%) | 7 (87.5) | 1 (12.5) | 8 (20.5) | 0.049 | | MODS, (%) | 9 (81.8) | 2 (18.2) | 11 (28.2) | 0.028 | | Laboratory results | | | | | | Hb, median (IQR) | 10.8 (2.6) | 11.3 (5.0) | 10.85 (3.6) | 0.794 | | WBC, median (IQR) | 10290 (6665) | 6210 (6758) | 8290 (7850) | 0.076 | | C-reactive protein, median (IQR) | 112 (82.85) | 66.05 (118.97) | 96.5 (103.4) | 0.143 | | Creatinine, median (IQR) | 0.66 (0.43) | 0.7 (0.21) | 0.675 (0.315) | 0.663 | | Total protein, median (IQR) | 53.6 (14.2) | 56.6 (7.38) | 54.8 (12.5) | 0.069 | | Albumin, median (IQR) | 20.3 (7.7) | 23.5 (9.12) | 20.9 (8.0) | 0.132 | | Presence of other infections/acute diseases at admission, (%) | 7 (41.2) | 10 (58.8) | 17 (43.6) | 0.163 | | Management and complications in the ICU | | | | | | Mechanical ventilation, (%) | 20 (69.0) | 9 (31.0) | 29 (74.4) | 0.002 | | Days of mechanical ventilation, median (IQR) | 24.0 (40.0) | 7.0 (14.5) | 17.0 (39.00) | 0.14 | | ARDS, (%) | 6 (85.7) | 1 (14.3) | 7 (17.9) | 0.098 | | ECMO, (%) | 2 (100) | 0 | 2 (5.1) | 0.49 | | Vasopressor infusion, (%) | 18 (85.7) | 3 (14.3) | 21 (53.8) | <0.001 | | Renal replacement therapy, (%) | 3 (100) | 0 | 3 (7.7) | 0.235 | | Hospital acquired infections, (%) | 9 (81.8) | 2 (18.2) | 11 (28.2) | 0.028 | | VAP, (%) | 6 (75.0) | 2 (25.0) | 8 (20.5) | 0.247 | | Catheter related infection, (%) | 3 (100) | 0 | 3 (7.7) | 0.235 | | Antituberculous therapy initiated in the ICU, (%) | 20 (60.6) | 13 (39.4) | 33 (84.6) | 0.077 | | Within 3 days of ICU admission, (%) | 13 (54.2) | 11 (45.8) | 24 (72.7) | 0.420 | | After the third day of ICU admission, (%) | 7 (77.8) | 2 (22.2) | 9 (27.3) | 0.420 | | Days until therapy initiation, mean (IQR) | 0 (4) | 0 (2) | 0 (4) | 0.545 | | Adjunctive corticotherapy, (%) | 0 | 5 (100) | 5 (12.8) | 0.015 |
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