Clinical Utility of a Structured Program to Reduce the Risk of Health-Related Quality of Life Impairment after Discharge from Intensive Care Unit: A Real-World Experience

Table 3

Main characteristics.

	PICS ()	No PICS ()	value	Before- group ()	value
Age (years)	66 ± 7	63 ± 8	0.07	64 ± 8	0.21
Female gender ()	15 (51.7%)	55 (42.3%)	0.36	30 (42.3%)	0.99
Need of ventilation support ()	17 (58.6%)	55 (42.3%)	0.11	36 (51.4%)	0.48
Perioperative complications^a ()	6 (20.7%)	20 (15.4%)	0.67	10 (14.3%)	0.84
Severe comorbidities^b ()	3 (10.3%)	13 (10.0%)	0.78	7 (10.0%)	0.82
Septic shock^c ()	5 (17.2%)	25 (19.2%)	0.80	15 (21.4%)	0.79
Coma^d ()	4 (13.8%)	16 (12.3%)	0.76	7 (10.0%)	0.74
Trauma ()	3 (10.3%)	38 (29.2%)	0.11	11 (15.7%)	0.13
Delirium ()	27 (93.1%)	—	<0.0001	39 (55.7%)	<0.0001
Mortality ()	20 (69.0%)	22 (16.9%)	<0.0001	19 (27.1%)	0.041

PICS versus no PICS. Patients (pooled population with PICS and no PICS) versus controls. ^aSevere bleeding, postoperative respiratory failure requiring ventilation, and haemodynamic instability. ^bDefined as Charlson index ≥ 4. ^cDiagnosed according to the 2016 Third International Consensus Definitions for Sepsis and Septic Shock. Secondary to polmonitis (), peritonitis (), central nervous system infection (), urinary tract infection (), cutaneous infection (), and gastroenteritis (). ^dDefined as a score of −4 to −5 on the RASS scale.