Research Article
Institutional Incidence of Severe tPA-Induced Angioedema in Ischemic Cerebral Vascular Accidents
Table 1
Baseline characteristics of all patients by angioedema status.
| | | Angioedema, (%), | No angioedema, (%), |
| | Age (years) | 79.0 (68.0–87.0) | 68.8 (28.0–98.0) |
| | Sex | | | | Male | 0 (0) | 64 (45) | | Female | 4 (100) | 79 (55) |
| | Race | | | | Caucasian | 3 (75) | 93 (65) | | Black | 1 (25) | 27 (19) | | Asian | 0 (0) | 3 (2) | | Hispanic | 0 (0) | 0 | | Unknown | 0 (0) | 20 (14) |
| | Coronary artery disease (CAD) | | | | Yes | 1 (25) | 34 (24) | | No | 3 (75) | 109 (76) |
| | Diabetes | | | | Yes | 1 (25) | 34 (24) | | No | 3 (75) | 109 (76) |
| | Atrial fibrillation | | | | Yes | 2 (50) | 44 (31) | | No | 2 (50) | 99 (69) |
| | Hypertension | | | | Yes | 4 (100) | 125 (87) | | No | 0 (0) | 18 (13) |
| | ACE inhibitor use | | | | Yes | 3 (75) | 40 (30) | | No | 1 (25) | 103 (70) |
| | Median NIHSS score | 10 | 9 |
| | Mean symptom onset to needle time (minutes) | 118.3 | 140.9 |
| | Area of ischemia on imaging | | | | Basal ganglia | 0 (0) | 6 (4) | | Middle cerebral artery (MCA) only | 3 (75) | 77 (54) | | Anterior cerebral artery (ACA) only | 0 (0) | 6 (4) | | Posterior cerebral artery (PCA) | 1 (25) | 17 (12) | | Both MCA and ACA | 0 (0) | 2 (1) | | None evidenced | 0 (0) | 35 (25) |
| | Median total length of stay (days) | 30 | 12 |
| | Death | | | | Yes | 1 (25) | 24 (17) | | No | 3 (75) | 119 (83) |
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