Anemia, Blood Transfusion, and Filter Life Span in Critically Ill Patients Requiring Continuous Renal Replacement Therapy for Acute Kidney Injury: A Case-Control Study
Table 1
Characteristics of all patients enrolled in the study, where cases were patients who required continuous renal replacement therapy in the intensive care unit and controls were critically ill patients who did receive renal replacement therapy. Cases and controls were matched for age, gender, APACHE II score, and admission category.
Variables
All patients (N = 197)
CRRT (N = 95)
No CRRT (N = 102)
value
Age (years), mean ± SD
61.4 ± 16.4
55.7 ± 15.3
63.0 ± 17.3
0.15
Male gender, N (%)
121 (61.4)
60 (62.5)
61 (60.4)
0.76
Body mass index (kg/m2), mean ± SD
31.5 ± 19.4
33.6 ± 26.6
29.3 ± 7.7
0.12
APACHE II score, mean ± SD
25.6 ± 6.1
25.9 ± 7.1
25.4 ± 7.5
0.63
Admission type, N (%)
0.14
Medical
176 (89.3)
90 (93.8)
86 (85.1)
Surgical
15 (7.6)
4 (4.2)
11 (10.9)
Trauma
6 (3.0)
2 (2.1)
4 (4.0)
Chronic illnesses, N (%)
Cardiac comorbidity
83 (42.1)
47 (49.0)
36 (35.6)
0.06
Respiratory comorbidity
43 (21.8)
21 (21.9)
22 (21.8)
0.99
Hepatic comorbidity
12 (6.1)
9 (9.4)
3 (3.0)
0.06
Renal comorbidity
42 (21.3)
28 (29.2)
14 (13.9)
0.009
Immunocompromised state
18 (9.1)
8 (8.3)
10 (9.9)
0.70
Diabetes
116 (58.9)
61 (63.5)
55 (54.5)
0.20
Hypertension
122 (61.9)
62 (64.6)
60 (59.4)
0.45
Sepsis on admission, N (%)
50 (25.4)
34 (35.4)
16 (15.8)
0.002
Shock on admission, N (%)
37 (18.8)
27 (28.1)
10 (9.9)
0.001
Requirement for mechanical ventilation, N (%)
181 (91.9)
90 (93.8)
91 (90.1)
0.35
Laboratory findings
Serum creatinine on admission (micromol/L), mean ± SD
175.7 ± 172.1
237.6 ± 213.8
116.8 ± 86.5
<0.001
Albumin on admission (g/L), mean ± SD
28.9 ± 5.9
29.0 ± 5.3
28.9 ± 6.4
0.98
Lactate on admission (mmol/L), mean ± SD
2.7 ± 2.8
3.3 ± 3.4
2.1 ± 1.8
0.002
Platelet count on admission (×109/L), mean ± SD
233.7 ± 141.5
199.2 ± 117.4
266.5 ± 154.7
0.001
Hemoglobin on admission (g/L), mean ± SD
112.7 ± 23.1
111.8 ± 18.7
113.6 ± 26.6
0.60
APACHE: Acute Physiology and Chronic Health Evaluation; SD: standard deviation.
