Review Article

Intravenous Fluid of Choice in Major Abdominal Surgery: A Systematic Review

Table 2

Characteristics of perioperative fluids included in this review.

FluidNa+K+ClCa2+Mg2+HCO3-BufferGlucose (g/L)OtherMolecular wt (kDa)/C2 : C6 ratioOsmolarityOncotic pressure (mmHg)pH (in vitro)Initial volume expansion (%)Persistence in the body (days)Maximal daily dose (per kg)

Plasma14051004.424.4Lactate 12857.4
0.9% NaCl (NSS)1541543086
3% NaCl51351310264.5
5% Dextrose502524.5
5% Dextrose/ 0.45%NaCl7777504064
Lactated Ringer solution (Hartmann’s solution, LRS)13041093Lactate 282736.5
Plasmalyte1405983Acetate 27 Gluconate 232947.4
Jonosteril13741101.61.2Acetate 36.8nana---
Ringer maleate (Ringerfundin)14541272.51Maleate 5 Acetate 24nana
G5K solution50306502HPO4 8Lactate 1850454na
4%–5% Albumin130–160130–16030920–297.180--
Dextran70154154na56–68na12028–421.5
6% HES 670/0.75 (hetastarch)154154670/4.5 : 130925–305.51004–620
6% HES 200/0.62 (Elohes)154154200/9 : 1na25–30na1106–720
6% HES 200/0.5 (Hesteril)154154200/5 : 1Na30–37na1003–433
6% HES 130/0.4 NSS (Voluven)154154130/9 : 130836na1002–350
6% HES 130/0.4 balanced solution (Volulyte)13741103Acetate 34130/9 : 1287nana1002–350
6% HES 70/0.5 in balanced solution (Hespander)105492.32.7Lactate 2070/3 : 1na1001–220
4% succinylated gelatin (Gelofusine)154125302747.1–7.7802–7

Note. Electrolyte concentrations, osmolarity, and pH may be subject to small differences in other reports. HES = hydroxyethyl starch; kDa = kilodalton.