Research Article
Early Driving Pressure Changes Predict Outcomes during Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome
| | Nonsurvivors | Survivors | values |
| VV-setting ECMO | (n = 15) | (n = 17) | | Blood flow (l/min) | 4.0 | 4.6 | 0.0799 | Rotation per minute (rpm) | 4160 | 3427 | 0.1163 | Sweep gas flow (l/min) | 3.967 | 3.882 | 0.8647 |
| Plateau pressure (mbar) | (n = 28) | (n = 28) | | Before ECMO | 32.2 ± 4.8 | 35.0 ± 6.7 | 0.0998 | 12 h after ECMO | 27.1 ± 4.1 | 25.6 ± 3.2 | 0.1496 |
| Positive end-expiratory pressure (mbar) | (n = 28) | (n = 28) | | Before ECMO | 15.0 ± 3.4 | 15.4 ± 3.1 | 0.7798 | 12 h after ECMO | 14.0 ± 2.8 | 15.3 ± 2.7 | 0.1049 |
| Mean airway pressure (mbar) | (n = 28) | (n = 28) | | Before ECMO | 22.7 ± 4.8 | 22.0 ± 4.1 | 0.7309 | 12 h after ECMO | 20.2 ± 2.5 | 19.2 ± 3.3 | 0.2278 |
| Respiratory rate (per minute) | (n = 28) | (n = 28) | | Before ECMO | 21 ± 5 | 23 ± 8 | 0.7076 | 12 h after ECMO | 15 ± 6 | 14 ± 5 | 0.4264 |
| Tidal volumes/ideal body weight (ml/kg) | (n = 28) | (n = 28) | | Before ECMO | 5.7 ± 2.3 | 6.3 ± 1.6 | 0.7875 | 12 h after ECMO | 3.3 ± 4.8 | 3.7 ± 1.8 | 0.5783 |
| Static compliance (ml/mbar) | (n = 28) | (n = 28) | | Before ECMO | 28 ± 11 | 25 ± 10 | 0.4976 | 12 h after ECMO | 22 ± 13 | 31 ± 18 | 0.0447 |
| Driving pressure (mbar) | (n = 28) | (n = 28) | | Before ECMO | 16.9 ± 3.8 | 18.4 ± 6.3 | 0.4976 | 12 h after ECMO | 13.0 ± 4.3 | 10.3 ± 3.0 | 0.0121 |
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