Research Article

Continuous Estimation of Cardiac Output in Critical Care: A Noninvasive Method Based on Pulse Wave Transit Time Compared with Transpulmonary Thermodilution

Figure 2

Comparison between COTPTD and COesCCO in patients with sepsis (a–c) and patients with neither sepsis nor trauma (d–f). (a) In patients with sepsis, correlation between COTPTD and COesCCO estimates at baseline was significant (r = 0.813, ), regression coefficient was 0.59, and the intercept was 1.82 l/min (COesCCO = 0.59 × COTPTD + 1.82 l/min); (d) in patients with neither sepsis nor trauma, correlation was significant (r = 0.669, ), regression coefficient was 0.41, and the intercept was 2.75 l/min (COesCCO = 0.41 × COTPTD + 2.75 l/min). In patients with sepsis (b) comparing COTPTD and COesCCO yielded a bias of 1.52 l/min and limits of agreement of −2.08 and +5.12 l/min; in patients with neither sepsis nor trauma (e), bias was 1.77 l/min and limits of agreement of −1.81 and +5.34 l/min. Estimates of the change in CO over the first 8 h (M8 h – Mmean baseline) was analyzed by four quadrant plots with regressions fitted. In patients with sepsis (c), COesCCO = 0.24 × COTPTD – 0.27 l/min, and for patients with neither sepsis nor trauma (f), COesCCO = 0.35 × COTPTD + 0.02 l/min.
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