Assessment of Metabolic Dysfunction in Sepsis in a Retrospective Single-Centre Cohort
Table 2
Unadjusted and SOFA-adjusted odds ratio for in-hospital mortality within 90 days of intensive care admission.
Variable within the first 24 hours
Unadjusted analyses
SOFA-adjusted analyses
OR [95%CI]
value
OR [95%CI]
value
Maximal lactatemia
1.31 [1.23; 1.40]
<0.001
1.17 [1.10; 1.25]
<0.001
Minimal glycaemia
0.85 [0.61; 1.17]
0.31
0.84 [0.60; 1.18]
0.32
Maximal glycaemia
0.95 [0.80; 1.13]
0.59
0.85 [0.70; 1.03]
0.089
Minimal temperature
0.85 [0.75; 0.96]
0.009
0.95 [0.83; 1.08]
0.41
Maximal temperature
0.91 [0.80; 1.03]
0.12
0.89 [0.77; 1.01]
0.076
Cholesterol level
0.57 [0.41; 0.80]
0.001
0.81 [0.59; 1.13]
0.21
Triglyceride level
1.02 [0.89; 1.16]
0.83
0.90 [0.77; 1.05]
0.16
Age
1.03 [1.02; 1.04]
<0.001
1.04 [1.03; 1.05]
<0.001
Charlson’s comorbidity score
1.22 [1.16; 1.28]
<0.001
1.24 [1.17; 1.32]
<0.001
CI, confidence interval; OR: odds ratio; SOFA, sequential organ failure assessment. Missing parameters were as follows: no patients lacked data for body temperature, age, and Charlson’s comorbidity score, 1 (0.1%) lacked data for glycaemia, 36 (3.8%) for lactatemia, and 151 (15.8%) for both cholesterolemia and triglyceridemia Bold values highlight the significant p values.
