Number of platelet concentrates per transfusion episode∗∗
Median (Q1, Q3)
1.0 (1.0, 2.0)
1.0 (1.0, 2.0)
1.0 (1.0, 1.0)
<0.001
Time to next platelet transfusion (days)
Median (Q1, Q3)
1.0 (1.0, 2.0)
1.0 (1.0, 2.0)
1.0 (1.0, 2.3)
0.006
Platelet increment (x106/L)
Median (Q1, Q3)
6000.0 (−5000.0, 24000.0)
2000 (−8000, 14000)
21000.0 (9000.0, 42000.0)
<0.001
Corrected count increment (x106/L)
Median (Q1, Q3)
2800.0 (−2000.0, 10800.0)
600.0 (−3700.0, 5800.0)
10300.0 (3800.0, 18800.0)
<0.001
∗For patients with missing data, the denominator is the number of patients with valid observations. For the calculation of percentages, only valid observations are used in the numerator and denominator. ∗∗Six units of single donor platelets prepared from whole blood were pooled to produce a single pooled platelet concentrate.∗∗∗Mixed indicates aggregate transfusions that were derived from transfusions with 2 or more different platelet products. APACHE: Acute Physiologic Assessment and Chronic Health Evaluation; CCI: corrected count increment DIC: disseminated intravascular coagulation; ICU: intensive care unit; INR: International Normalized Ratio, Q1: first quartile, Q3: third quartile.