Use of mNUTRIC-Score for Nutrition Risk Assessment and Prognosis Prediction in Critically Ill Patients with COVID-19: A Retrospective Observational Study
Table 3
Comparison of each item among 28-day survivors and nonsurvivors.
Clinical characteristics
Survivors, n = 27
Nonsurvivors, n = 71
value
Female n, (%)
10 (37%)
21 (29.6%)
0.478
Male n, (%)
17 (63%)
50 (70.4%)
Age, mean
49.51 ± 12.73
60.15 ± 12.91
≤0.001
Comorbidities
1 (0–4)
1 (0–7)
0.101
Charlson comorbidity index
2 (0–4)
3 (0–9)
≤0.001
Severity of disease
SOFA score
6.22 ± 2.53
8.25 ± 2.56
≤0.001
APACHE II
14.59 ± 7.11
20.76 ± 6.09
≤0.001
Biochemical
Glucose (mg/dL)
154 (77–533)
164 (45–452)
0.387
Creatinine (mg/dL)
0.83 (0.39–20.23)
1.48 (0.30–13.20)
≤0.001
BUN (mg/dL)
22.60 (10.50–137)
34 (9–108)
≤0.001
Albumin (g/dL)
2.59 ± 0.44
2.54 ± 0.50
0.667
C-reactive protein (mg/dL)
197.37 ± 167.50
199.95 ± 123.78
0.934
Arterial blood gas
pH
7.35 ± 0.14
7.30 ± 0.14
0.156
PaCO2 (mmHg)
38 (14–163)
45 (13–114)
0.694
Bicarbonate (mmol/L)
23.37 ± 7.13
22.50 ± 5.83
0.538
Lactate (mmol/L)
1.80 (0.60–4.30)
2.10 (0.90–7)
0.056
PaO2/FiO2 (mmHg)
79 (31–277)
74 (41–366)
0.565
Outcomes
Mechanical ventilation (days)
9 (3–40)
7 (1–27)
0.024
Total mNUTRIC-Score, median (IQR), points
2 (0–7)
5 (0–8)
≤0.001
mNutric-Score level, n (%)
4 (14.8%)
42 (59.2%)
≤0.001
Hospital length of stay (days)
17 (10–96)
11 (2–28)
≤0.001
Initial nutrition therapy (hours)
76 (12–240)
72 (24–240)
0.713
Initial time of nutrition therapy
≤48 h, n (%)
11 (40.7%)
24 (33.8%)
0.490
>48 h, n (%)
16 (59.3%)
25 (35.2%)
Complications, n (%)
Acute kidney injury, n (%)
10 (37%)
52 (73.2%)
≤0.001
Upper gastrointestinal bleeding, n (%)
2 (7.4%)
4 (5.6%)
0.744
Vasopressors, n (%)
11 (40.7%)
39 (54.9%)
0.209
Abbreviations: APACHE II, Acute Physiology and Chronic Health Evaluation II; BUN, blood urea nitrogen; mNUTRIC-Score, modified Nutrition Risk in the Critically Ill-Score; IQR, interquartile range; PaCO2, arterial partial carbon dioxide pressure; PaO2/FiO2 ratio, partial pressure of arterial oxygen to fraction of inspired oxygen; SOFA, Sequential Organ Failure Assessment.
