Research Article

Heart-Protective Mechanical Ventilation in Postoperative Cardiosurgical Patients

Table 3

Changes in hemodynamic profile in patients from the interventional group not requiring catecholamines for three hours of study, median (25th; 75th percentile), n = 50.

DataHours in ICU
#1#2#3

HR (bpm)80 (69; 86)77 (71; 85)76 (72; 86) = 0.7
p3-2 = 0.5
 = 0.97

MAP (mmHg)85 (79; 97)83.5 (76; 91)73 (69; 82) <0.001
 = 0.2

PAP mean (mmHg)16 (13; 18)17 (14; 19)19 (16; 22) <0.001
 = 0.06

CVP (mmHg)6 (5; 8)6 (4; 7)8 (6; 9) <0.001
 = 0.7

PAWP (mmHg)7 (5; 9)8 (6; 9)10 (7; 11) <0.001
 = 0.1

CO (l × min−1)5.05 (4.30; 5.90)5.20 (4.40; 5.90)4.65 (4.30; 5.30) = 0.001
<0.001
 = 0.21

CI (l × min−1 × m2−1)2.6 (2.4; 2.9)2.7 (2.4; 3.0)2.5 (2.2; 2.7) = 0.002
<0.001
 = 0.2

SV (ml)66 (54; 80)65 (54; 78)60 (54; 67) = 0.002
<0.001
 = 0.9

SI (ml × m2−1)34 (29; 39)35 (29; 40)31 (29; 35) = 0.009
<0.001
 = 0.5

SVR (dyn × sec−1 × cm−5)1254 (1077; 1509)1142 (1071; 1426)1088 (963; 1341) <0.001
 = 0.001
 = 0.06

PVR (dyn × sec−1 × cm−5)127.5 (111; 163)134.5 (109; 157)152.5 (136; 183) <0.001
 = 0.98

HR: heart rate; MAP: mean arterial pressure; PAP: pulmonary artery pressure; CVP: central venous pressure; PAWP: pulmonary artery wedge pressure; CO: cardiac output; CI: cardiac index; SV: stroke volume; SI: stroke index; SVR: systemic vascular resistance; PVR: pulmonary vascular resistance; : Wilcoxon test.