Research Article

Heart-Protective Mechanical Ventilation in Postoperative Cardiosurgical Patients

Table 4

Changes in respiratory mechanics data in patients from the control group at three hours of the study, median (25th; 75th percentile), n = 24.

DataHours in ICU
#1#2#3

MV (l × min−1)10.5 (10.1; 12.0)6.2 (5.8; 7.0)6.2 (5.8; 7.0) <0.001
>0.5

Va (l × min−1)9.2 (8.6; 10.1)5.2 (5.0; 5.8)5.2 (4.9; 5.8) <0.001
 = 0.54

(cmH2O)10.5 (10.0; 11.0)9.0 (8.0; 10.0)9.0 (8.0; 10.0) <0.001
 = 0.54

(cmH2O)22.0 (20.0; 23.0)21.0 (20.0; 22.0)21.5 (20.0; 22.0) = 0.062
 = 0.65
 = 0.002

R (cmH2O × l−1 × sec−1)7.7 (6.9; 8.6)7.4 (6.8; 8.3)7.9 (7.1; 8.4) = 0.95
 = 0.032
 = 0.086

С (ml × cmH2O−1)53.5 (49.3; 56.8)52.7 (49.9; 56.8)53.4 (50.8; 57.2) = 0.27
 = 0.11
 = 0.92

Vds/Vte (%)15.0 (14.0; 17; 0)15.0 (13.0; 16.0)15.0 (13.0; 16.0) = 0.36
 = 1
 = 0.36

ΔP (cmH2O)14.1 (13.2; 17.0)14.3 (12.9; 17.6)14.0 (12.7; 17.6) = 0.3
 = 0.06
 = 0.98

MV: minute ventilation; Va: alveolar ventilation; : mean airway pressure; : inspiratory pressure; R: resistance; C: compliance; Vds/Vte: dead space/tidal volume ratio; ΔР: driving pressure; P: Wilcoxon test.