Responsiveness Index versus the RASS-Based Method for Adjusting Sedation in Critically Ill Patients

Table 2

Outcome and adverse event data.

	RI group	RASS group	value
Median days alive in 30 days without mechanical ventilation (range)	7.90 (0–28.82)	15.23 (0–29.25)	0.72
Median ICU length of stay in hours (range)	416 (101–938)	302 (73–1204)	0.69
At least one of the predefined adverse events	12/15	11/16	0.69
Hypertension	6/15	0/16	0.01
Hypotension	1/15	4/16	0.33
Tachycardia	4/15	6/16	0.70
Tachypnea	1/15	2/16	1.00
Unplanned removal of catheter	2/15	0/16	0.23
Restlessness	8/15	5/16	0.29
Other adverse events	3/15	5/16	0.69

Adverse event data are presented as the number of patients with at least one adverse event related to sedation. Other adverse events are gas exchange deficiency, minor skin irritation caused by electrodes, hemodynamic instability, and unplanned extubation. Wilcoxon rank-sum test was used for days alive, log-rank test for ICU length of stay, and for the other data, values were estimated with Fisher’s exact test.