Responsiveness Index versus the RASS-Based Method for Adjusting Sedation in Critically Ill Patients

Table 3

RI, SE, and RASS at the time of propofol and oxycodone boluses.

	RI group	RASS group	value
Propofol
No. of boluses, N	261	201
RI	32.5 (0–100)	12.5 (0–100)	<0.001
SE	55 (5–92)	30 (3–91)	<0.001
RASS	−4 (−5 to 1)	−3 (−5 to 2)	<0.001
Oxycodone
No. of boluses, N	313	328
RI	33 (0–100)	10 (0–100)	<0.001
SE	51 (8–91)	30 (2–92)	<0.001
RASS	−4 (−5 to 1)	−3 (−5 to 2)	<0.001

Presented values are medians (range) of RI, SE, and RASS samples collected at the time when bolus doses of propofol or oxycodone were administered intravenously. RI: Responsiveness Index, SE: State Entropy, RASS: Richmond Agitation-Sedation Scale. One patient in the RASS group received midazolam instead of propofol, and one patient in the RASS group received fentanyl infusion. These patients were excluded from this analysis.