Critical Care Research and Practice

Research Article

Clinical Outcomes of Critically Ill Patients Using Inhaled Nitric Oxide (iNO) during Intrahospital Transport

Table 1

The demographics, underlying conditions, admission diagnoses, laboratory data, and therapeutic management during the ICU stay.


	Group 1 (n = 156)	Group 2 (n = 65)	value

Age, years (mean ± SD^b)	50.92 ± 19.826	50 ± 18.822	0.751
Weight, kg (mean ± SD)	80.763	90.523	0.655
Male gender, no. (%)	112/156 (72.4%)	47/65 (72.3%)	0.985
Admission diagnosis, no. (%)
Sepsis	47/156 (30.1%)	28/65 (43.1%)	0.174
Multiple traumas	67/156 (43.6%)	24/65 (36.9%)	0.179
Other	41/156 (26.3%)	13/65 (20%)	0.97
ICU scores at admission (units, mean ± SD)
APACHE^c score	26.49 ± 4.7	25.8 ± 4.28	0.34
TISS^d score	29.81 ± 9.51	27.57 ± 5.54	0.07
Laboratory data during iNO treatment in ICU
WBC^e (1000 cells/μL, mean ± SD)	16.582 ± 9.523	14.986 ± 8.652	0.245
Hemoglobin (g\dL)	11.528 ± 3.033	11.420 ± 2.586	0.801
Serum urea (mmol/L)	58.32 ± 53.086	54.29 ± 43.592	0.590
Serum creatinine (mmol/L)	1.626 ± 2.892	1.286 ± 0.903	0.354
Blood glucose level (mg/dL)	156.79 ± 62.036	161.85 ± 61.739	0.581
Underlying conditions, no. (%)
CIHD^f	36/156 (23.1%)	13/65 (20.1%)	0.83
COPD^g	24/156 (15.4%)	20/65 (30.8%)	0.02
HTN^h	31/156 (19.9%)	18/65 (27.7%)	0.04
Otherⁱ	64/156 (41.7%)	14/65 (21.5%)	0.03
Therapeutic management and diagnostic tests during ICU stay, no. (%)
Vasopressor support	119/156 (76.3%)	46/65 (69.2%)	0.275
Steroid treatment	87/156 (56.4%)	40/65 (61.5%)	0.482
ECHO study findings
Left ventricle dysfunction (moderate/severe)	47/156 (30.1%)	20/65 (29.7%)	0.297
Right ventricle dysfunction	50/156 (32%)	18/65 (28%)	0.616
Pulmonary hypertension (moderate/severe)	62/156 (40.3%)	21/65 (33.3%)	0.757

Group 1: critically ill patients who were not transported outside of the ICU during their hospitalization period. Group 2: critically ill patients who were transported outside of the ICU during iNO treatment during their hospitalization period. Data are considered statistically significant if . Other diagnoses include intracerebral hemorrhage, cardiogenic shock, eclampsia, SAH, NSTEMI, and pulmonary edema. Vasopressor support: norepinephrine continuous infusion; steroid treatment: concomitant hydrocortisone administration. ^aICU: intensive care unit. ^bSD: standard deviation. ^cAPACHE: Acute Physiology and Chronic Health Evaluation on admission to ICU.^{. d}TISS: Therapeutic Intervention Scoring System on admission to ICU. ^eWBC: white blood cells. ^fCIHD: chronic ischemic heart disease. ^gCOPD: chronic obstructive pulmonary disease. ^hHTN: chronic hypertension. ^IOther: diabetes mellitus II, dyslipidemia, alcohol abuse, fat embolism, and pulmonary embolism.