Postintubation Decline in Oxygen Saturation Index Predicts Mortality in COVID-19: A Retrospective Pilot Study

Table 1

Clinical characteristics of the COVID-19 patients with acute hypoxic respiratory failure requiring intubation.

Characteristic	Survivors	Nonsurvivors
Age in years (SD)	58.1 (16.3)	68.3 (10.8)	0.0036
Gender
Female (n (%))	7 (21.21%)	15 (42.86%)	0.0565
Male (n (%))	26 (78.79%)	20 (57.14%)	0.0565
Race
White (n (%))	9 (31.03%)	7 (20.59%)	0.6544
African American (n (%))	14 (48.28%)	18 (52.94%)	0.6544
Asian	0 (0%)	1 (2.94%)	0.6544
Others (n (%))	0 (0%)	1 (2.94%)	0.6544
Unknown	6 (20.69%)	7 (20.59%)	0.6544
Ethnicity
Hispanic	14 (42.42%)	9 (25.71%)	0.1455
Non-Hispanic	19 (57.58%)	26 (74.29%)	0.1455
BMI	31.89 (8.43)	33.48 (7.66)	0.4731
SOFA	8 (2.30)	9 (3.42)	0.4768
APACHE II	21.2 (6.8)	20.3 (10.5)	0.8314
Charlson comorbidity index	3.5 (2.9)	5.9 (2.2)	0.0004
Myocardial infarction	1 (3.03%)	10 (28.57%)	0.0043
Congestive heart failure	4 (12.12%)	9(25.71%)	0.1543
Peripheral vascular disease	3 (9.09%)	5 (14.29%)	0.5064
Cerebrovascular disease	5 (15.15%)	4 (11.43%)	0.6507
Chronic obstructive lung disease	3 (9.09%)	6 (17.14%)	0.3275
Liver disease	1 (3.03%)	0 (0%)	0.4821
Chronic kidney disease	2 (6.06%)	10 (28.57%)	0.0149
Diabetes mellitus	13 (39.39%)	26 (74.29%)	0.0036
Laboratory parameters
C-reactive protein (mg/dL)	119.4 (121.0)	113.8 (110.9)	0.8532
D-dimer (mog/mL)	1.6 (2.4)	3.2 (6.8)	0.2059
Hemoglobin (mg/dL)	12.1 (2.2)	11.9 (1.7)	0.7908
Procalcitonin	1.2 (3.1)	3.0 (5.8)	0.1084
Creatinine (mg/dL)	1.2 (1.3)	1.9 (1.9)	0.0734
Respiratory parameters
PEEP (cm H2O)	10.2 (3.3)	11.8 (3.1)	0.045
FiO2 (%)	69.3 (21.7)	73.6 (21.1)	0.4113
MAP (cm. H2O)	14.3 (3.5)	16.5 (3.7)	0.0183
Tidal volume (ml)	446.3 (41.7)	420.5 (65.7)	0.0565
Days ventilated	13.9 (9.1)	14.7 (8.3)	0.7304
ICU length of stay (days)	13.7 (7.7)	15.8 (8.5)	0.3652
Hospital length of stay (days)	21.6 (10.2)	16.9 (8.7)	0.0859

Values are presented as mean (%), mean (SD) when normally distributed, or median (IQR).