Research Article
Postintubation Decline in Oxygen Saturation Index Predicts Mortality in COVID-19: A Retrospective Pilot Study
Table 1
Clinical characteristics of the COVID-19 patients with acute hypoxic respiratory failure requiring intubation.
| Characteristic | Survivors | Nonsurvivors | |
| Age in years (SD) | 58.1 (16.3) | 68.3 (10.8) | 0.0036 |
| Gender | Female (n (%)) | 7 (21.21%) | 15 (42.86%) | 0.0565 | Male (n (%)) | 26 (78.79%) | 20 (57.14%) | 0.0565 |
| Race | White (n (%)) | 9 (31.03%) | 7 (20.59%) | 0.6544 | African American (n (%)) | 14 (48.28%) | 18 (52.94%) | 0.6544 | Asian | 0 (0%) | 1 (2.94%) | 0.6544 | Others (n (%)) | 0 (0%) | 1 (2.94%) | 0.6544 | Unknown | 6 (20.69%) | 7 (20.59%) | 0.6544 |
| Ethnicity | Hispanic | 14 (42.42%) | 9 (25.71%) | 0.1455 | Non-Hispanic | 19 (57.58%) | 26 (74.29%) | 0.1455 | BMI | 31.89 (8.43) | 33.48 (7.66) | 0.4731 | SOFA | 8 (2.30) | 9 (3.42) | 0.4768 | APACHE II | 21.2 (6.8) | 20.3 (10.5) | 0.8314 | Charlson comorbidity index | 3.5 (2.9) | 5.9 (2.2) | 0.0004 | Myocardial infarction | 1 (3.03%) | 10 (28.57%) | 0.0043 | Congestive heart failure | 4 (12.12%) | 9(25.71%) | 0.1543 | Peripheral vascular disease | 3 (9.09%) | 5 (14.29%) | 0.5064 | Cerebrovascular disease | 5 (15.15%) | 4 (11.43%) | 0.6507 | Chronic obstructive lung disease | 3 (9.09%) | 6 (17.14%) | 0.3275 | Liver disease | 1 (3.03%) | 0 (0%) | 0.4821 | Chronic kidney disease | 2 (6.06%) | 10 (28.57%) | 0.0149 | Diabetes mellitus | 13 (39.39%) | 26 (74.29%) | 0.0036 |
| Laboratory parameters | C-reactive protein (mg/dL) | 119.4 (121.0) | 113.8 (110.9) | 0.8532 | D-dimer (mog/mL) | 1.6 (2.4) | 3.2 (6.8) | 0.2059 | Hemoglobin (mg/dL) | 12.1 (2.2) | 11.9 (1.7) | 0.7908 | Procalcitonin | 1.2 (3.1) | 3.0 (5.8) | 0.1084 | Creatinine (mg/dL) | 1.2 (1.3) | 1.9 (1.9) | 0.0734 |
| Respiratory parameters | PEEP (cm H2O) | 10.2 (3.3) | 11.8 (3.1) | 0.045 | FiO2 (%) | 69.3 (21.7) | 73.6 (21.1) | 0.4113 | MAP (cm. H2O) | 14.3 (3.5) | 16.5 (3.7) | 0.0183 | Tidal volume (ml) | 446.3 (41.7) | 420.5 (65.7) | 0.0565 | Days ventilated | 13.9 (9.1) | 14.7 (8.3) | 0.7304 | ICU length of stay (days) | 13.7 (7.7) | 15.8 (8.5) | 0.3652 | Hospital length of stay (days) | 21.6 (10.2) | 16.9 (8.7) | 0.0859 |
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Values are presented as mean (%), mean (SD) when normally distributed, or median (IQR).
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