Critical Care Research and Practice

Research Article

Postintubation Decline in Oxygen Saturation Index Predicts Mortality in COVID-19: A Retrospective Pilot Study

Table 3

Unadjusted and multivariate adjusted odds ratio of death for Crs, PaO₂/FiO₂, OI, SpO₂/FiO₂, and OSI.


Day 0	Unadjusted OR (95% CI)	Multivariate OR (95% CI)	val (unadj)	val (adj)

Crs (per 10 ml/cm H₂O decrease)	1.644 (0.951, 2.839)	1.318 (0.960, 2.456)	0.0737	0.383
PaO₂/FiO₂ (per 10 mmHg decrease)	1.020 (0.951, 1.083)	1.010 (0942, 1.083)	0.6193	0.8289
OI (per 10 cm H₂O/mmHg increase)	1.041 (0.961, 1.116)	1.030 (0.942, 1.12)	0.3593	0.5039
SpO₂/FiO₂ (per 10 unit decrease)	1.051 (0.961, 1.161)	1.062 (0.961, 1.172)	0.3908	0.2285
OSI (per cm H₂O increase)	1.107 (0.996, 1.230)	1.119 (0.996, 1.258)	0.0587	0.0588

Day 3	Unadjusted OR (95% CI)	Multivariate OR (95% CI)	val (unadj)	val (adj)

Crs (per 10 ml/cm H₂O decrease)	1.930 (1.149, 3.219)	1.708 (1.00, 2.943)	0.0124	0.0512
PaO₂/FiO₂ (per 10 mmHg decrease)	1.104 (1.020, 1.207)	1.116 (1.020, 1.231)	0.0164	0.0229
OI (per 10 cm H₂O/mmHg increase)	1.093 (1.020, 1.207)	1.0937 (1.010, 1.184)	0.0142	0.0242
SpO₂/FiO₂ (per 10 mmHg decrease)	1.138 (1.041, 1.243)	1.116 (1.020, 1.231)	0.0048	0.0235
OSI (per cm H₂O increase)	1.092 (1.017, 1.173)	1.088 (1.007, 1.177)	0.0156	0.0333

Day 7	Unadjusted OR (95% CI)	Multivariate OR (95% CI)	val (unadj)	val (adj)

Crs (per 10 ml/cm H₂O decrease)	2.119 (1.207, 3.772)	2.004 (1.072, 3.740)	0.0094	0.0282
PaO₂/FiO₂ (per 10 mmHg decrease)	1.149 (1.041, 1.268)	1.172 (1.051, 1.318)	0.0053	0.0045
OI (per 10 cm H₂O/mmHg increase)	1.267 (1.105, 1.452)	1.357 (1.138, 1.613)	0.0006	0.0006
SpO₂/FiO₂ (per 10 unit decrease)	1.293 (1.138, 1.466)	1.344 (1.161, 1.568)	<0.0001	0.0001
OSI (per cm H₂O increase)	1.275 (1.120, 1.451)	1.346 (1.346, 1.581)	0.0002	0.0003