The Value of Combining Carbon Dioxide Gap and Oxygen-Derived Variables with Lactate Clearance in Predicting Mortality after Resuscitation of Septic Shock Patients
Table 3
Baseline characteristics of the study population.
The studied variables
All patients (N = 456)
Survivors (N = 292)
Nonsurvivors (N = 164)
value
Age (years)
63.2 ± 6.9
61.4 ± 4.6
65.8 ± 7.2
0.001
Gender (male)
328 (71.9%)
216 (73.9%)
112 (68.3%)
0.34
Diabetes mellitus, n (%)
287 (62.9)
188 (64.4)
99 (60.4)
0.04
Chronic kidney disease, n (%)
218 (47.8)
117 (40.1)
101 (61.6)
0.02
Chronic heart failure, n (%)
127 (28)
83 (28.4)
44 (26.8)
0.34
Coronary artery disease, n (%)
141 (30.9)
89 (30.4)
52 (31.7)
0.42
Previous cerebrovascular stroke, n (%)
26 (5.7)
18 (6.2)
8 (4.9)
0.7
Left ventricle EF (%)
52.3 ± 6.8
51.6 ± 8.7
49.4 ± 4.8
0.31
Source of sepsis, n (%)
Pneumonia
227 (49.8)
154 (52.7)
73 (44.5)
0.38
Urinary
113 (24.8)
64 (21.9)
49 (29.8)
Abdominal
82 (17.9)
59 (20.2)
23 (14.1)
Soft tissue
34 (7.5)
21 (7.2)
13 (9.7)
APACHE II score
24.3 ± 9.7
18.2 ± 3.7
34.3 ± 6.8
<0.001
SOFA score at admission
6.4 ± 1.6
5.8 ± 3.1
7.3 ± 1.4
0.001
SOFA score after 48 hours
6.2 ± 3.6
4.2 ± 1.8
9.4 ± 3.1
<0.001
Need for dialysis
68 (14.9%)
30 (10.3%)
38 (23.2%)
0.02
Length of stay (days)
5.6 ± 2.4
6.8 ± 2.1
3.6 ± 1.7
<0.001
Hemoglobin (g/dL)
10.6 ± 2.3
10.9 ± 1.2
9.82 ± 2.3
0.51
Platelet count (×103/ml)
134.2 ± 52.6
146.7 ± 38.3
128.6 ± 52.7
0.2
INR
1.3 ± 0.71
1.2 ± 0.62
1.1 ± 0.45
0.61
Creatinine (mg/dL)
1.4 ± 0.3
1.2 ± 0.2
1.6 ± 0.6
0.041
Bilirubin (mg/dL)
2.1 ± 1.2
1.8 ± 1.3
2.4 ± 1.6
0.13
Albumin (mg/dL)
3.6 ± 1.4
3.6 ± 1.3
3.2 ± 1.6
0.02
AST(U/L)
21.4 ± 2.6
20.9 ± 2.8
26.3 ± 3.4
0.015
ALT(U/L
26.8 ± 3.1
24.4 ± 2.7
27.4 ± 3.4
0.22
APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; INR: international normalized ratio; ALT: alanine transaminase; AST: aspartate transferase. Data are presented as mean (±SD) or N (%).
