The Value of Combining Carbon Dioxide Gap and Oxygen-Derived Variables with Lactate Clearance in Predicting Mortality after Resuscitation of Septic Shock Patients
Table 4
Hemodynamic and blood gases’ variables of the studied patients.
The studied variables
All patients
Survivors
Nonsurvivors
value
Initial values (T0)
MAP (mmHg)
42.3 ± 5.4
43.6 ± 6.7
41.4 ± 3.1
0.43
Heart rate (beats/min)
106 ± 26.3
102 ± 38.3
114 ± 29.7
0.19
Temperature (°C)
37.2 ± 1.7
37.1 ± 1.9
37 ± 1.87
0.32
Norepinephrine (μg/kg/minute)
0.41 ± 0.28
0.36 ± 0.21
0.67 ± 0.08
<0.001
Blood lactate (mg/dl)
53.8 ± 18.9
51.4 ± 15.2
57.8 ± 18.7
0.12
PaO2 (mmHg)
61.4 ± 24.4
62.6 ± 12.3
60.2 ± 26.4
0.74
CaO2 (ml/dL)
12.6 ± 1.3
12.1 ± 1.8
11.8 ± 1.7
0.25
CvO2 (ml/dL)
7.6 ± 1.7
8.2 ± 1.4
7.1 ± 1.3
0.003
CavO2 (ml/dL)
4.3 ± 1.3
4.4 ± 1.6
4.9 ± 1.1
0.023
ScvO2 (%)
57.6 ± 9.6
61.4 ± 10.3
52.6 ± 8.8
0.003
ER O2 (%)
36 ± 8.2%
35 ± 8.1%
40 ± 7.3%
0.002
PaCO2 (mmHg)
46.3 ± 8.6
37.4 ± 7.6
38.4 ± 8.7
0.571
PvCO2 (mmHg)
38.4 ± 7.4
46.3 ± 8.4
46.4 ± 10.2
0.81
PvaCO2 (mmHg)
9.1 ± 3.2
9.2 ± 3.4
8.3 ± 2.8
0.32
PvaCO2/CavO2
2.1 ± 0.72
2.2 ± 0.81
1.8 ± 0.15
0.013
Follow-up values (T6)
MAP (mmHg)
62.7 ± 12.4
69.8 ± 5.4
60.6 ± 4.8
<0.001
Norepinephrine (μg/kg/minute)
0.82 ± 0.38
0.28 ± 0.23
1.02 ± 0.11
<0.001
Dopamine (μg/kg/minute)
5.63 (3.32–13.4)
4.6 (3.1–9.41)
6.34 (5.47–13.42)
0.06
Fluid intake (liters)
3.84 (2.62–6.24)
2.73 (2.42–4.35)
3.26 (2.94–6.31)
0.03
Lactate T6 (mg/dl)
49.4 ± 24.7
36.3 ± 14.4
73.4 ± 30.4
<0.001
PaO2 (mmHg)
84.2 ± 38.4
89.7 ± 31.2
71.7 ± 29.4
0.044
CaO2 (ml/dL)
13.7 ± 1.8
13.9 ± 1.4
12.7 ± 1.61
0.42
CvO2 (ml/dL)
8.3 ± 1.6
8.2 ± 1.7
8.7 ± 1.5
0.103
CavO2 (ml/dL)
4.6 ± 1.4
4.9 ± 1.4
4.1 ± 1.3
0.004
ScvO2 (%)
65.8 ± 9.7
71.3 ± 11.2
64.4 ± 8.4
0.038
ER O2 (%)
36.4 ± 8.9%
37 ± 9.4%
32.7 ± 9.5%
0.004
PaCO2 (mmHg)
41.7 ± 5.8
35.6 ± 4.3
36.6 ± 7.3
0.42
PvCO2 (mmHg)
36.2 ± 6.2
40.5 ± 4.3
45.3 ± 6.12
0.002
PvaCO2 (mmHg)
6.2 ± 4.6
4.7 ± 3.62
8.3 ± 4.7
<0.001
PvaCO2/CavO2
1.4 ± 1.1
1.2 ± 0.72
2.1 ± 1.13
<0.001
Lactate T12 (mg/dl)
37.8 ± 13.2
21.6 ± 8.7
57.6 ± 16.3
<0.001
MAP: mean arterial pressure; PaO2: arterial oxygen tension; CaO2: arterial oxygen content; CvO2: central venous oxygen content; CavO2: arteriovenous oxygen content difference; ScvO2%: central venous oxygen saturation; ER O2: oxygen extraction ratio; PaCO2: arterial carbon dioxide tension; PvCO2: venous carbon dioxide tension; PvaCO2: CO2 gap.
