The Value of Combining Carbon Dioxide Gap and Oxygen-Derived Variables with Lactate Clearance in Predicting Mortality after Resuscitation of Septic Shock Patients

Table 5

Changes of the studied variables with resuscitation.

The studied variables	Survivors	Nonsurvivors
SOFA score change	−2.0 (−1.9 to −1.4)	3 (2.1–3.1)	<0.001
Norepinephrine dose change	−0.06 (−01 to 0.2)	0.1 (0.01–0.11)	<0.001
∆lactate (%)	−29.4 (−35 to −26)	26.9 (24–41)	<0.001
ΔCavO2 (%)	14 (12% −27)	−21 (−20 to −8)	<0.001
ΔPvaCO2 (%)	−57 (−49 to −26)	−8 (−12 to 23)	<0.001
ΔPvaCO2/CavO2 (%)	−71 (−54 to −28)	7 (4–51)	<0.001

Data are presented as median and interquartile range (IQR). SOFA change = SOFA at 48 hours − admission SOFA. Norepinephrine dose change = dose at T6 − dose at T0. Lactate, CavO₂, PvaCO₂, PvaCO₂/CavO₂% change = T6 − T0/T0.