The Value of Combining Carbon Dioxide Gap and Oxygen-Derived Variables with Lactate Clearance in Predicting Mortality after Resuscitation of Septic Shock Patients

Table 7

ROC analysis of studied variables in predicting mortality.

ROC analysis	Lactate	PvaCO2	PvaCO2/CavO2	Combined lactate-PvaCO2
Cutoff	40	6	1.4	20.5
Area under the curve	0.902	0.791	0.793	0.930
Sensitivity	92.7%	71%	76%	93%
Specificity	75.3%	77%	70%	98%
PPV	67.9%	63%	58%	84%
NPP	94.8%	82%	84%	96%
Accuracy	81.6%	75%	72%	91%
LR+	3.8	3.0	2.5	9.7
LR−	0.1	0.4	0.3	0.1

ROC: receiver operating characteristics; PPV: positive predictive value; NPP: negative predictive value; LR: likelihood ratio.