Serum NT-Pro-BNP versus Noninvasive Bedside Inotropic Index in Paediatric Shock: A Contest of Myocardial Performance in Response to Fluid Loading
Table 1
Subject characteristics.
Subject characteristics
Fluid nonresponders (n = 26)
Fluid responders (n = 42)
value
n
%
n
%
Age in months (median, IQR)
27.00 (8.75–75.50)
51.00 (12.00–126.00)
0.180
Gender (male)
14
53.84
20
47.62
0.334
Shock category
Septic shock
9
34.62
6
14.29
0.026
Dengue shock
6
23.08
23
54.76
Others (hypovolemia and hemorrhagic)
11
42.31
13
30.95
Nutritional status (BW/ideal BW)
Malnutrition (z < −3SD)
4
15.38
6
14.29
0.383c
Undernourished (−3SD < z < −2SD)
5
19.23
7
16.67
Normal (−2SD < z < +2SD)
11
42.31
21
50.00
Overweight (+2SD < z < +3SD)
2
7.69
0
0.00
Obese (z > +3SD)
4
15.38
8
19.05
Total fluid loading
<20 ml/kg BW
6
23.08
11
26.19
0.972c
20–<40 ml/kg BW
13
50.00
20
47.62
40–<60 ml/kg BW
5
19.23
8
19.05
>60 ml/kg BW
2
7.69
3
7.14
Inotropic use, yes
10
38.46
22
52.38
0.534
Preloading MAP percentile (median, IQR)
30.00 (7.50–65.00)
50.00 (20.00–72.50)
0.567
Preloading NT-pro-BNP, normalb
7
26.92
29
69.05
0.001
Preloading SMII, normal
19
73.08
14
33.33
0.004
Preloading LVEDVIb (median, IQR)
70.75 (57.05–78.25)
67.20 (56.78–76.20)
0.757
BW: body weight; MAP: mean arterial pressure; SMII: Smith–Madigan inotropic index; LVEDVI: left ventricular end-diastolic volume. Categorical data were analysed using chi-square unless stated otherwise, numerical data were analysed using independent Kruskal–Wallis test, and value <0.05; apreloading MAP percentage from 64 subjects; bpreloading NT-pro-BNP percentage from 64 subjects; cFisher’s exact test; dindependent sample T-test.
