Research Article

Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support

Table 1

Baseline characteristics of the study population.

CharacteristicsMeans ± SD

Age (years)72.6 ± 14.3
Sex (F/M)13 (43.3%)
17 (56.7%)
Weight (Kg)63.04 ± 14.28
Height (cm)157.5 ± 10.3
BMI25.4 ± 5.2
Neck circumference (cm)48.8 ± 5.4
Mallampati score1.6 ± 0.6
Epworth sleepiness scale9.6 ± 5.90
SnoringNo, 19 (63.3%)
Yes, 11 (36.7%)
Apnea reported by patientNo, 25 (83.3%)
Yes, 5 (16.7%)
Days of stay in ICU8.6 ± 3.11
Days of NIV5.6 ± 2.76
SBP (systolic blood pressure) (mmHg)130.8 ± 17.1
DBP (diastolic blood pressure (mmHg)75.2 ± 9.4
HR (heart rate)89.1 ± 12
RR (respiratory rate)25.7 ± 4.7
SaO2 oximeter (%)94 ± 3
AHI (Apnea-Hypopnea Index)14.3 ± 14
IDO (Oxygenation Index)6.6 ± 5.9
SO2 average (%)91.9 ± 4.3
SO2 lower (%)73.4 ± 15.2
pH7.32 ± 0.02
pCO2 (mmHg)53.7 ± 10.4
PO2 (mmHg)75.4 ± 13.8
HCO3 (mmol/L)27.2 ± 6
EB2.9 ± 5.3
PaO2/FiO2 (mmHg)197.3 ± 38.9
FVC (pre)1.4 ± 0.53
FEV1,0 (pre)0.88 ± 0.4
FEV1,0/FVC (pre)49.8 ± 26.6
PEF (pre)2.1 ± 1.02
FVC (post)1.45 ± 0.51
FEV1,0 (post)0.9 ± 0.37
FEV1,0/FVC (pot)50.8 ± 24.4
PEF (post)2.4 ± 1.4
Tidal volume (ml)447.7 ± 67.6
Levels of EPAP (cmH2O)6.1 ± 0.4
Levels of IPAP programmed maximum (cmH2O)19.7 ± 0.9
Levels of IPAP (cmH2O)13.1 ± 4.9
Leak (cmH2O)17.9 ± 7.2
Inspiratory time (sec)0.8 ± 0.2
Vmin (L/min)10.3 ± 4.1
RAMP (msec)3 ± 0.2
ComorbidityNo, 16 (53.3%)
Yes, 14 (46.7%)
Diabetes mellitus-type II4 (13.3%)
Hypertension10 (33.3%)
None16 (53.3%%)
Orotracheal intubationYes, 2 (6.7%)
Not 28 (93.3%)
Affected lung quadrantsNone (13) (43.3%)
1 quadrant (13) (43.3%)
2 quadrants (4) (13.3%)
AHI (Apnea-Hypopnea Index)<5 (6) (20%)
5–15 (13) (43.3%)
>15 (11) (36.7%)

Continuous variables are presented as mean ± SD. Categorical variables are presented as No. (%).