Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support
Table 2
The characteristics of group’s severity according to AHI.
Variables
Apnea-Hypopnea Index <5
Apnea-Hypopnea Index 5–15
Apnea-Hypopnea Index >15
Value
(n = 6)
(n = 13)
(n = 11)
Age (years)
66.5 ± 18.7
71.7 ± 14.5
77 ± 11.4
0.354
Weight (Kg)
64 ± 6.3
58.4 ± 10.2
67.9 ± 19.8
0.275
Height (cm)
157.3 ± 8.8
156.6 ± 9.9
158.7 ± 12.2
0.891
BMI
26.2 ± 5.5
23.7 ± 2.8
26.9 ± 6.9
0.291
Days of stay in ICU
7.8 ± 3.2
9.08 ± 3.9
8.4 ± 2.0
0.722
Days of NIV
4.8 ± 1,7
5.9 ± 3.8
5.8 ± 1.7
0.721
SBP (systolic blood pressure) (mmHg)
133.3 ± 11.2
128.8 ± 14.6
131.8 ± 22.9
0.853
DBP (diastolic blood pressure (mmHg)
78.1 ± 6.1
74 ± 6.5
75 ± 13.6
0.685
HR (heart rate)
99 ± 18.6
86.6 ± 5.9
86.6 ± 11.6
0.076
RR (respiratory rate)
25.8 ± 2.9
26.8 ± 4.8
24.2 ± 5.4
0.432
SaO2
94.6 ± 3.1
92.6 ± 1.7
94.5 ± 3.1
0.155
Neck circumference (cm)
42.4 ± 2,9
49.1 ± 5.2
52 ± 3.4
0.001∗
Epworth scale
2 ± 1
9.4 ± 4,8
14.2 ± 3.6
0.001∗
Mallampati score
1.5 ± 0,5
1.4 ± 0,5
1.9 ± 0,8
0.001∗
Snoring
3 of 6
4 of 13
4 of 11
0.700
Apnea reported by patient
0 of 6
2 of 13
8 of 11
0.300
Comorbidity
3 of 6
6 of 13
5 of 11
0.900
pH
7.33 ± 0.04
7.33 ± 0.02
7.33 ± 0,03
0.913
pCO2 (mmHg)
47.8 ± 11.5
55.53 ± 12.1
54.7 ± 6.7
0.307
PO2 (mmHg)
77.4 ± 11.1
72.3 ± 13.4
77.8 ± 16.0
0.588
HCO3 (mmol/L)
24.3 ± 4.9
27.7 ± 6.8
28.1 ± 5.7
0.433
EB
0.27 ± 4,5
3.64 ± 6,1
3.3 ± 4,6
0.419
PaO2/FiO2 (mmHg)
202.6 ± 21,6
185 ± 40.7
208.8 ± 42.6
0.318
FVC (pre)
1.32 ± 0,3
1.33 ± 0,5
1.54 ± 0,7
0.595
FEV∗1,0 (pre)
0.8 ± 0,2
0.82 ± 0,4
0.99 ± 0,5
0.520
FEV∗1,0/FVC (pre)
58.7 ± 10.2
61.2 ± 15.0
61.2 ± 12,2
0.921
PEF (pre)
1.74 ± 0,7
2.02 ± 0,8
2.42 ± 1,3
0.406
FVC (post)
1.36 ± 0,3
1.37 ± 0,5
1.59 ± 0,6
0.525
FEV∗1,0 (post)
0.82 ± 0,3
0.83 ± 0,4
1 ± 0.5
0.517
FEV∗1,0/FVC (post)
0.68 ± 7,2
1.98 ± 7,4
2.13 ± 5,1
0.901
PEF (post)
1,94 ± 0,8
2,6 ± 2,0
2,48 ± 1,1
0.677
Tidal volume (ml)
546.6 ± 231.7
413,8 ± 81.7
513.6 ± 238.8
0.262
Levels of EPAP (cmH2O)
6 ± 0
6 ± 0
6.1 ± 0.6
0.436
Levels of maximum programmed IPAP (cmH2O)
20 ± 1.6
19.5 ± 0.9
19.8 ± 0,6
0.668
Levels of IPAP patient (cmH2O)
16.3 ± 2.7
16.6 ± 2.2
16.8 ± 1.3
0.875
Leak (cmH2O)
20.1 ± 6.2
17.6 ± 7.1
16.9 ± 8.1
0.678
Inspiratory time (sec)
0.78 ± 0.2
0.88 ± 0.2
0.79 ± 0.1
0.335
Vmin (L/min)
10.6 ± 1.4
8.6 ± 3.0
12 ± 5.6
0.129
RAMP (msec)
3 ± 0
3 ± 0.3
3 ± 0
0.536
∗Statistical significance at p < 0.05: statistically significant differences in neck circumference (cm), Epworth scale, and Mallampati score.