Research Article

Hospital Mortality and Resource Implications of Hospitalisation with COVID-19 in London, UK: A Prospective Cohort Study

Table 2

Admission and most abnormal laboratory values for the study population, by location of admission.

Study population (n = 429)Treated only on ward (n = 353)Treated in ICU (n = 76)Normal range
AdmissionMost abnormalAdmissionMost abnormalAdmissionMost abnormal

Haemoglobin (g·l−1)128 (110–141)110 (87–125)127 (110–140)113 (97–129)134 (114–148)78 (68–94)115–155
WBC (×109·l−1)6.7 (5.2–9.3)9.3 (6.9–13.3)6.5 (5.0–8.8)8.6 (6.5–11.0)8.2 (6.5–11.2)19.5 (12.4–28.0)4.0–11.0
Neutrophils (×109·l−1)5.2 (3.7–7.4)7.4 (5.3–11.2)4.9 (3.6–7.0)6.8 (4.9–9.1)6.7 (4.6–9.4)16.8 (10.1–23.2)2.2–6.3
Lymphocytes (×109·l−1)1.0 (0.7–1.4)0.8 (0.5–1.1)1.0 (0.7–1.4)0.8 (0.6–1.1)1.0 (0.8–1.3)0.7 (0.5–0.8)1.3–4.0
Platelets (×109·l−1)213 (161–278)187 (139–237)210 (159–279)189 (142–243)219 (172–274)174 (110–217)150–450
CRP (mg·l−1)75 (28–143)159 (81–299)61 (22–119)143 (66–218)134 (84–239)385 (310–487)<5
Creatinine (μmol·l−1)92 (68–130)102 (77–207)91 (68–128)97 (74–143)96 (69–150)324 (108–533)45–120
AST (IU·l−1)43 (29–69)70 (44–122)39 (27–59)59 (39–92)63 (39–102)196 (104–396)10–50
GGT (IU·l−1)47 (26–94)74 (40–182)44 (25–88)64 (35–126)64 (39–113)237 (106–433)1–55
Bilirubin (μmol·l−1)8 (5–11)10 (7–15)7 (5–11)9 (6–13)9 (6–13)15 (10–23)3–20
Creatine kinase (U·l−1)368 (89–1553)546 (108–1870)374 (88–1628)311 (78–1628)318 (90–1363)773 (168–2091)<150
LDH (U·l−1)476 (355–670)522 (353–748)365 (229–496)350 (252–496)564 (426–757)628 (466–805)<240
Troponin T (ng·l−1)25 (11–54)35 (15–85)25 (11–60)27 (11–65)26 (10–51)51 (22–174)<14
Ferritin (μg·l−1)914 (298–1596)1039 (399–2374)666 (258–1374)877 (304–1512)1157 (487–1777)1630 (683–3423)13–150
D-Dimers (ng·l−1)1850 (805–4090)1850 (805–4090)1315 (610–2470)1315 (610–2470)3240 (1160–6950)3240 (1160–6950)<500
Lactate (mmol·l−1)1.5 (1.1–2.0)1.7 (1.3–2.5)1.5 (1.1–2.1)1.5 (1.2–2.2)1.5 (1.1–1.9)2.3 (1.8–4.8)<2

Data are reported as median (IQR). Abbreviations: WBC, white blood cells; CRP, C-reactive protein; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; LDH, lactate dehydrogenase. Admission laboratory tests were not performed or available for the following number of patients: haemoglobin 1/429 (<1%), white blood cells 2/429 (<1%), neutrophils 1/429 (<1%), lymphocytes 1/429 (<1%), platelets 8/429 (2%), C-reactive protein 2/429 (<1%), creatinine 1/429 (<1%), AST 35/429 (8%), GGT 18/429 (4%), bilirubin 5/429 (1%), creatinine kinase 345/429 (80%), LDH 363/429 (85%), troponin 271/429 (63%), ferritin 318/429 (74%), D-dimers 309/429 (72%), and lactate 86/429 (20%). Subsequent laboratory tests were not performed for the following number of patients: haemoglobin 8/429 (2%), white blood cells 9/429 (2%), neutrophils 7/429 (2%), lymphocytes 9/429 (2%), platelets 8/429 (2%), C-reactive protein 6/429 (1%), creatinine 6/429 (1%), AST 25/429 (6%), GGT 14/429 (3%), bilirubin 9/429 (2%), creatinine kinase 339/429 (79%), LDH 356/429 (83%), troponin 266/429 (62%), ferritin 302/429 (70%), D-dimers 309/429 (72%), and lactate 115/429 (27%).