The Positive and Negative Effects of Calcium Supplementation on Mortality in Septic ICU Patients Depend on Disease Severity: A Retrospective Study from the MIMIC-III

Table 2

Differences in clinical characteristics between survivors and nonsurvivors in septic patients with iCa records at the first ICU admission (hospital mortality).

	Total (n = 2,694)	Survivors (n = 2,194)	Nonsurvivors (n = 500)	value
Age (median, Q1∼Q3)	64.46 (52.05–77.19)	63.38 (51.17–75.25)	70.3 6 (57.23–81.73)	<0.001
Sex (male; n, %)	1579 (58.61%)	1291 (58.84%)	288 (57.60%)	0.611
Ca^2+ on first ICU admission (median, Q1∼Q3)	1.10 (1.04∼1.15)	1.10 (1.04∼1.15)	1.09 (1.00∼1.14)	0.006
Congestive heart failure (n, %)	596 (22.12%)	465 (21.19%)	131 (26.20%)	0.015
Cardiac arrhythmias (n, %)	979 (36.34%)	737 (33.59%)	242 (48.40%)	<0.001
Pulmonary circulation (n, %)	212 (7.87%)	174 (7.93%)	38 (7.60%)	0.804
Hypertension (n, %)	1532 (56.87%)	1255 (57.20%)	277 (55.40%)	0.463
Chronic pulmonary (n, %)	604 (22.42%)	482 (21.97%)	122 (24.40%)	0.240
Diabetes uncomplicated (n, %)	565 (20.97%)	459 (20.92%)	106 (21.20%)	0.890
Diabetes complicated (n, 3%)	156 (5.79%)	126 (5.74%)	30 (6.00%)	0.824
Hypothyroidism (n, %)	328 (12.18%)	261 (11.90%)	67 (13.40%)	0.353
Renal failure (n, %)	434 (16.11%)	334 (15.22%)	100 (20.00%)	0.009
Liver disease (n, %)	443 (16.44%)	292 (13.31%)	151 (30.20%)	<0.001
Metastatic cancer (n, %)	166 (6.16%)	116 (5.29%)	50 (10%)	<0.001
Coagulopathy (n, %)	488 (18.11%)	346 (15.77%)	142 (28.40%)	<0.001
Fluid electrolyte disturbance (n, %)	1278 (47.44%)	950 (43.30%)	328 (65.60%)	<0.001