Critical Care Research and Practice / 2022 / Article / Tab 2 / Research Article
The Positive and Negative Effects of Calcium Supplementation on Mortality in Septic ICU Patients Depend on Disease Severity: A Retrospective Study from the MIMIC-III Table 2 Differences in clinical characteristics between survivors and nonsurvivors in septic patients with iCa records at the first ICU admission (hospital mortality).
Total (n = 2,694) Survivors (n = 2,194) Nonsurvivors (n = 500) valueAge (median, Q 1 ∼Q 3 ) 64.46 (52.05–77.19) 63.38 (51.17–75.25) 70.3 6 (57.23–81.73) <0.001 Sex (male; n , %) 1579 (58.61%) 1291 (58.84%) 288 (57.60%) 0.611 Ca2+ on first ICU admission (median, Q 1 ∼Q 3 ) 1.10 (1.04∼1.15) 1.10 (1.04∼1.15) 1.09 (1.00∼1.14) 0.006 Congestive heart failure (n , %) 596 (22.12%) 465 (21.19%) 131 (26.20%) 0.015 Cardiac arrhythmias (n , %) 979 (36.34%) 737 (33.59%) 242 (48.40%) <0.001 Pulmonary circulation (n , %) 212 (7.87%) 174 (7.93%) 38 (7.60%) 0.804 Hypertension (n , %) 1532 (56.87%) 1255 (57.20%) 277 (55.40%) 0.463 Chronic pulmonary (n , %) 604 (22.42%) 482 (21.97%) 122 (24.40%) 0.240 Diabetes uncomplicated (n , %) 565 (20.97%) 459 (20.92%) 106 (21.20%) 0.890 Diabetes complicated (n , 3%) 156 (5.79%) 126 (5.74%) 30 (6.00%) 0.824 Hypothyroidism (n , %) 328 (12.18%) 261 (11.90%) 67 (13.40%) 0.353 Renal failure (n , %) 434 (16.11%) 334 (15.22%) 100 (20.00%) 0.009 Liver disease (n , %) 443 (16.44%) 292 (13.31%) 151 (30.20%) <0.001 Metastatic cancer (n , %) 166 (6.16%) 116 (5.29%) 50 (10%) <0.001 Coagulopathy (n , %) 488 (18.11%) 346 (15.77%) 142 (28.40%) <0.001 Fluid electrolyte disturbance (n , %) 1278 (47.44%) 950 (43.30%) 328 (65.60%) <0.001