The Positive and Negative Effects of Calcium Supplementation on Mortality in Septic ICU Patients Depend on Disease Severity: A Retrospective Study from the MIMIC-III

Table 5

The difference in the 28-day and hospital mortality in septic patients with or without calcium supplementation under different iCa intervals.

iCa range (mmol/L)	Calcium supplementation (n = 593)			Nonsupplementation (n = 435)
	iCa at the first ICU admission (median, Q1∼Q3)	28-day mortality (%)	Hospital mortality (%)	iCa at the first ICU admission (median, Q1∼Q3)	28-day mortality (%)	Hospital mortality (%)
≤1.00	0.94 (0.89∼0.98)	16.37	18.10	0.95 (0.90∼0.97)	29.72	32.43
1.01∼1.10	1.06 (1.04∼1.09)	16.52	17.80	1.07 (1.04∼1.09)	14.56	14.56
1.11∼1.15	1.13 (1.12∼1.14)	14.52	14.52	1.13 (1.12∼1.14)	10.69	10.69
1.16–1.20	1.18 (1.17∼1.19)	13.79	15.52	1.18 (1.17∼1.20)	15.15	15.15
≥1.20	1.24 (1.23∼1.27)	15.25	15.25	1.24 (1.22∼1.30)	20.00	21.43
Total	1.09 (1.02∼1.14)	15.18	16.36	1.12 (1.06∼1.18)	15.40	16.09