Research Article

Predictors of ICU Mortality among Mechanically Ventilated Patients: An Inception Cohort Study from a Tertiary Care Center in Addis Ababa, Ethiopia

Table 1

Baseline characteristics of mechanically ventilated patients admitted to the adult intensive care unit of Tikur Anbessa Hospital, Addis Ababa, Ethiopia from September 2019 to September 2020, displayed against their ICU outcome using the chi-square (X2), t-test, and Mann–Whitney U test.

VariablesTotal (n = 160)Survivors (n = 63)Nonsurvivors (n = 97) value

SexMale
Female
75 (46.9)
85 (53.1)
28 (44.4)
35 (56.6)
47 (48.5)
50 (51.5)
0.66
Age years(Mean ± SD)38.9 ± 16.236.4 ± 14.4 yrs40.5 ± 17.2 yrs0.123
Source of admissionOR
Emergency
Wards
70 (43.8)
38 (23.8)
48 (30.0)
39 (61.9)
9 (14.3)
13 (20.6)
31 (32.0)
29 (29.9)
35 (36.1)
<0.01
Hospital stay before admission, daysMedian (IQR)6 (2–14)10 (5–15)4 (1–12)0.01
Place of admissionMICU
SICU
66 (41.3)
94 (58.7)
10 (18.9)
53 (81.1)
56 (57.7)
41 (42.3)
<0.01
MPM II score(Mean ± SD)39.6 ± 25.521.9 ± 14.646.5 ± 26.4<0.01
ICU priority levelLevel 1
Level 2
Level 3
Level 4
77 (48.1)
5 (3.1)
47 (29.4)
31 (19.4)
52 (82.5)
2 (3.2)
8 (12.7)
1 (1.6)
25 (25.8)
3 (3.1)
39 (40.7
30 (30.9)
<0.01
GCS at ICU admission<8/7T
>8/8T/Sedated
35 (21.9)
125 (78.1)
3 (4.8)
60 (95.2)
32 (33.0)
65 (77.0)
<0.01
IndicationOperative
Non-operative
68 (42.5)
92 (57.5)
41 (65.1)
22 (34.9)
27 (29.0)
70 (71.0)
<0.01
Admission diagnosisNeurologic
Respiratory
Cardiovascular
Hematologic
Renal
Gastrointestinal
85 (53.1)
97 (60.6)
57 (35.6)
45 (28.1)
41 (25.6)
25 (15.6)
45 (71.4)
25 (39.7)
7 (11.1)
8 (12.7)
8 (12.7)
6 (9.5)
40 (41.2)
72 (74.2)
50 (51.5)
37 (38.1)
33 (34.0)
19 (19.6)
<0.01
Initial mode of ventilationAC/VC
SIMV/VC
AC/PC
Others
87 (56.5)
41 (26.6)
15 (9.7)
11 (7.1)
23 (37.7)
26 (42.6)
4 (6.6)
8 (13.1)
64 (66.0)
15 (15.5)
11 (11.8)
3 (3.3)
<0.01
Serum albumin, g/dl(Mean ± SD)2.5 ± 0.83.0 ± 12.3 ± 0.6<0.01
ComorbidityImmunosuppression
Hypertension
Retroviral infection
Congestive heart failure
Diabetes
90 (56.3)
32 (20.1)
10 (6.3)
14 (8.8)
10 (6.3)
51 (52.6)
11 (17.5)
2 (3.2)
3 (4.8)
2 (3.2)
39 (61.9)
21 (21.9)
8 (8.2)
11 (11.3)
8 (8.2)
0.59

Process and outcome of care.