Critical Care Research and Practice


Publishing date
01 Jun 2012
Submission deadline
02 Dec 2011

1Department of Intensive Care, Experimental Medicine Laboratory, CHU de Charleroi, Charleroi, Belgium

2Department of Intensive Care, Erasmus Medical Center, Erasmus University of Rotterdam, Rotterdam, The Netherlands

3Servicio de Terapia Intensiva, Sanatorio Otamendi y Miroli, Buenos Aires, Argentina



Microcirculation is the part of the circulation where oxygen, nutrients, hormone, and waste products are exchanged between circulating blood and parenchymal cells. It includes not only vessels with a diameter < 100 μm but also interactions between compounds of blood (circulating cells and coagulation factors) and vessels (endothelium and glycocalyx). All compounds of the microcirculation could be altered in critically ill patients, especially during sepsis. In these patients, persistence of these alterations is associated with a poor outcome. Due to the important role of the microcirculation for oxygen and nutrients exchanges, a better comprehension and its modulation could decrease morbidity and mortality in critically ill patients.

We invite the authors to submit original research or review articles that will contribute to better define, understand, and treat the alterations of microcirculation in critically ill patients. We are interested in articles, which explore aspects of (patho-) physiology, biochemistry, and immunity of all compounds of the microcirculation: muscle, endothelium, glycocalyx, and blood cells (white cells, red cells, platelets, and microparticles). Potential topics include, but are not limited to:

  • Assessment of microcirculation
  • Epidemiology of alterations of microcirculation in critically ill patients
  • Translational medicine: from animal to human
  • Links between microcirculation and macrocirculation
  • Effects of fluids on microcirculation
  • Effects of catecholamines on microcirculation
  • Alterations of microcirculation in cirrhosis
  • Alterations of microcirculation during ischemia/reperfusion process
  • Microcirculation in brain injury
  • Microcirculation in sepsis
  • Microcirculation in hemorrhagic shock
  • Microcirculation in trauma
  • Microcirculation in cardiac failure
  • Microcirculation in cardiac arrest
  • Link between coagulation and microcirculation
  • Effects of hypothermia on microcirculation
  • Effects of transfusion on microcirculation
  • Hormonal effects on microcirculation
  • Role of blood cells on microcirculation
  • Platelets as an actor of microcirculation
  • Microcirculation and diabetes mellitus

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2012
  • - Article ID 867176
  • - Editorial


Michael Piagnerelli | Can Ince | Arnaldo Dubin
  • Special Issue
  • - Volume 2012
  • - Article ID 842545
  • - Research Article

Impact of Enzymatic Degradation of the Endothelial Glycocalyx on Vascular Permeability in an Awake Hamster Model

S. A. Landsverk | A. G. Tsai | ... | M. Intaglietta
  • Special Issue
  • - Volume 2012
  • - Article ID 654381
  • - Clinical Study

Microcirculation and Macrocirculation in Cardiac Surgical Patients

Elli-Sophia Tripodaki | Athanasios Tasoulis | ... | Serafim Nanas
  • Special Issue
  • - Volume 2012
  • - Article ID 372956
  • - Clinical Study

The Microcirculation Is Unchanged in Neonates with Severe Respiratory Failure after the Initiation of ECMO Treatment

Anke P. C. Top | Erik A. B. Buijs | ... | Can Ince
  • Special Issue
  • - Volume 2012
  • - Article ID 702956
  • - Review Article

Alterations of the Erythrocyte Membrane during Sepsis

Yasmina Serroukh | Sarah Djebara | ... | Michael Piagnerelli
  • Special Issue
  • - Volume 2012
  • - Article ID 121752
  • - Clinical Study

Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients

Namkje A. R. Vellinga | E. Christiaan Boerma | ... | Can Ince
  • Special Issue
  • - Volume 2012
  • - Article ID 102483
  • - Research Article

Comparison of Different Methods for the Calculation of the Microvascular Flow Index

Mario O. Pozo | Vanina S. Kanoore Edul | ... | Arnaldo Dubin
  • Special Issue
  • - Volume 2012
  • - Article ID 536852
  • - Clinical Study

Persistent Sepsis-Induced Hypotension without Hyperlactatemia: A Distinct Clinical and Physiological Profile within the Spectrum of Septic Shock

Glenn Hernandez | Alejandro Bruhn | ... | Can Ince
Critical Care Research and Practice
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Acceptance rate20%
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Impact Factor1.7
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