The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

Table 10

Comparison of experimental groups in terms of LDH levels.

Comparison Groups	P Value
Control x Low Dose Pitavastatin	1.000
Control x High Dose Pitavastatin	0.053
Control x TNF-α	0.053
Control x Low Dose Pitavastatin + TNF-α	0.053
Control x High Dose Pitavastatin + TNF-α	0.053
Control x DMSO	0.052
Low Dose Pitavastatin x High Dose Pitavastatin	0.128
Low Dose Pitavastatin x TNF-α	0.109
Low Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.259
Low Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.078
Low Dose Pitavastatin x DMSO	0.336
High Dose Pitavastatin x TNF-α	0.010
High Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.025
High Dose Pitavastatin x High Dose Pitavastatin + TNF-α	1.000
High Dose Pitavastatin x DMSO	0.748
Low Dose Pitavastatin + TNF-αx TNF-α	0.520
Low Dose Pitavastatin + TNF-αx High Dose Pitavastatin + TNF-α	0.016
Low Dose Pitavastatin + TNF-αx DMSO	0.109
High Dose Pitavastatin + TNF-αx TNF-α	0.010
High Dose Pitavastatin + TNF-αx DMSO	0.748
TNF-α x DMSO	0.748

LDH, lactate dehydrogenase; TNF-α, tumor necrosis factor-α; DMSO, dimethyl sulfoxide.