Research Article
Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome
Table 2
Genotype distribution among the study population.
| | | | Total
(n=459) | Minor Allele Frequency(%) | Hardy-Weinberg equilibrium (P value) |
| | CYP2C192 | GG(1/1) | 228(49.7%) | 30.7 | 0.941 | | | GA(1/2) | 180(39.2%) | | | | | AA(2/2) | 51(11.1%) | | | | CYP2C193 | GG(1/1) | 416(90.6%) | 4.7 | 0.592 | | | GA(1/3) | 43(9.4%) | | | | | AA(3/3) | 0(0%) | | | | CYP2C1917 | CC(1/1) | 447(97.4%) | 1.4 | 0.558 | | | CT(1/17) | 11(2.4%) | | | | | TT(17/17) | 1(0.2%) | | | | PON1 | QQ(AA) | 63(13.7%) | 37.8 | 0.927 | | | QR(AG) | 221(48.1%) | | | | | RR(GG) | 175(38.1%) | | | | ABCB1 | CC | 168(36.6%) | 38.7 | 0.802 | | | CT | 227(49.5%) | | | | | TT | 64(13.9%) | | |
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