New Insights into the Association between Fibrinogen and Coronary Atherosclerotic Plaque Vulnerability: An Intravascular Optical Coherence Tomography Study
Table 2
Coronary angiographic findings and OCT characteristics according to plaque vulnerability.
Ruptured plaque group
Nonrupture with TCFA group
Nonrupture and non-TCFA group
t/χ2
P
ACS-IFC (%)
2.271
0.321
No
15 (88.2)
11 (73.3)
108 (88.5)
Yes
2 (11.8)
4 (26.7)
14 (11.5)
Vasa vasorum
1.826
0.401
No
16 (94.1)
12 (80.0)
111 (91.0)
Yes
1 (5.9)
3 (20.0)
11 (9.0)
Thrombus
31.431
<0.001
No
4 (23.5)
10 (66.7)
107 (87.7)
Yes
13 (76.5)
5 (33.3)
15 (12.3)
Macrophage accumulation
32.148
<0.001
0
3 (17.6)
3 (20.0)
79 (64.8)
1
7 (41.2)
7 (46.7)
25 (20.5)
2
5 (29.4)
4 (26.7)
18 (14.8)
3
1 (5.9)
1 (6.7)
0 (0.0)
4
1 (5.9)
0 (0.0)
0 (0.0)
MLA(mm2)
3.28±1.89
3.51±2.08
3.50±1.97
0.090
0.914
NLA(mm2)
11.60±3.73
10.78±3.03
10.19±3.01
1.777
0.173
Rate of stenosis
81.12±15.89
75.67±13.35
72.93±17.14
1.870
0.158
Calcified nodule
1.137
0.547
No
17 (100.0)
15 (100.0)
113 (92.6)
Yes
0 (0.0)
0 (0.0)
9 (7.4)
Target vessel
5.880
0.208
LAD
10 (58.8)
10 (66.7)
95 (77.9)
LCX
2 (11.8)
3 (20.0)
6 (4.9)
RCA
5 (29.4)
3 (13.3)
21 (17.2)
Lesion length
8.45±4.07
10.29±3.92
9.64±3.39
1.204
0.303
Location of target plaque
0.804
1.000
Pro
11 (64.7)
10 (66.7)
80 (65.6)
Mid
6 (35.3)
5 (33.3)
40 (32.8)
Distal
0 (0.0)
0 (0.0)
2 (1.6)
Values are presented as n (%), or mean ± SD; ACS-IFC: Acute Coronary Syndrome with Intact Fibrous Cap; FCT, fibrous cap thickness; MLA, minimal lumen area; NLA, normal lumen area; Pro, proximal.
