Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses

Table 1

The 91 differentially expressed genes were identified in AA samples compared to EA samples. (The differentially expressed genes were ranked from the smallest to the largest of adjusted value).

DEGs	Gene name
Upregulated genes ()	SLAMF8, SERPINA1, VAMP8, C3AR1, CD52, CD84, CCR1, FCGBP, CD14, FCGR1B, ITGB2, LAPTM5, PIK3AP1, C1QB, APOE, KYNU, CTSS, RAC2, CD37, TYROBP, IGLC1, ACP5, TNFSF13B, CD53, CCL19, LY86, NPL, CCL18, IGLV1-44, BCAT1, SPP1, FCGR2B, C1QC, FABP5, PTPRC, MS4A7, CHI3L1, PLXNC1, GIMAP2, IER3, ADAMDEC1, CSF2RB, ITGAM, NCF2, CEMIP, CLEC5A, IGKC, CD86, IGLL3P, IGJ, CXCR4, CXCL2, RNASE6, FPR3, MSR1, KCNT2, EVI2B, IGHM, MMP9
Downregulated genes ()	ANGPTL1, TMEM35, BTC, BAG2, SLMAP, MBNL1-AS1, ATP1A2, PIP5K1B, C3orf70, SH3BGR, CNTN4, SBSPON, CAB39L, ACADL, ACTN2, NEXN, PDZRN3, PLD5, SLC22A3, KCNMA1, TTLL7, BAMBI, PPP1R1A, NTN1, AMIGO2, APCDD1, MYBL1, CNN1, RBP4, TOX2, CNTN1, LGR6