Research Article

Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses

Table 3

The significant signal pathways of differentially expressed genes (DEGs).

PathwayTermCount value

Upregulated genes
KEGG_PATHWAYhsa05150: Staphylococcus aureus infection72.40-07
KEGG_PATHWAYhsa04145: phagosome79.36-05
KEGG_PATHWAYhsa04670: leukocyte transendothelial migration62.60-04
KEGG_PATHWAYhsa05133: pertussis55.28-04
KEGG_PATHWAYhsa04060: cytokine-cytokine receptor interaction70.001252687
KEGG_PATHWAYhsa04062: chemokine signaling pathway60.002299717
KEGG_PATHWAYhsa05134: legionellosis40.002506044
BioCartah_blymphocytePathway: B lymphocyte cell surface molecules30.003628217
KEGG_PATHWAYhsa04610: complement and coagulation cascades40.005025012
KEGG_PATHWAYhsa05323: rheumatoid arthritis40.009854418
KEGG_PATHWAYhsa05152: tuberculosis50.011906527
KEGG_PATHWAYhsa04672: intestinal immune network for IgA production30.023560079
KEGG_PATHWAYhsa04380: osteoclast differentiation40.028350582
KEGG_PATHWAYhsa05416: viral myocarditis30.033703679
KEGG_PATHWAYhsa04514: cell adhesion molecules (CAMs)40.034833291
Downregulated genes

No significant signal pathway ( value < 0.05) available.