Research Article
The Effect of Early Treatment with Intravenous Magnesium Sulfate on the Incidence of Cardiac Comorbidities in Hospitalized Stroke Patients
Table 1
Dichotomized demographic and clinical characteristics of patients in magnesium and placebo groups.
| | Overall group () | Patients in magnesium group () | Patients in placebo group () | value (Mg vs. Pl) |
| | Age (mean, SD) | 69.5 (13.4) | 69.8 (13.4) | 69.2 (13.5) | 0.41 | | Sex female (, percent) | 472 (42.0) | 243 (43.1) | 229 (40.8) | 0.44 | | Diagnosis, (%) | | | | | | Acute cerebral ischemia | 809 (71.8) | 406 (71.9) | 403 (71.8) | 0.21 | | Intracranial hemorrhage | 277 (24.6) | 144 (25.5) | 133 (23.7) | | Stroke mimic | 39 (3.5) | 14 (2.5) | 25 (4.5) | | Race, (%) | | | | | | White | 854 (75.8) | 429 (75.9) | 425 (75.8) | 0.63 | | Black/African American | 157 (13.9) | 74 (13.1) | 83 (14.8) | | Asian | 102 (9.1) | 55 (9.7) | 47 (8.4) | | Other | 12 (1.0) | 6 (1.1) | 6 (1.1) | | | Ethnicity–Hispanic, (%) | 270 (24.0) | 135 (23.9) | 135 (24.1) | 0.99 | | Medical history | | | | | | Hypertension, (%) | 877 (78.0) | 441 (78.2) | 436 (77.7) | 0.89 | | Diabetes, (%) | 250 (22.2) | 138 (24.6) | 112 (19.9) | 0.62 | | Hyperlipidemia, (%) | 533 (47.4) | 274 (48.8) | 259 (45.9) | 0.34 | | Atrial fibrillation, (%) | 254 (22.6) | 125 (22.3) | 129 (22.9) | 0.83 | | CAD, (%) | 245 (21.8) | 127 (22.6) | 118 (20.9) | 0.52 | | MI, (%) | 125 (11.1) | 63 (11.2) | 62 (11.0) | 0.93 | | CABG, (%) | 30 (2.7) | 17 (3.0) | 13 (2.3) | 0.47 | | Prior stroke, (%) | 86 (7.6) | 39 (7.0) | 47 (8.3) | 0.43 | | Tobacco use, (%) | 199 (17.7) | 103 (18.4) | 96 (17.0) | 0.31 | | Any alcohol use, (%) | 443 (39.4) | 225 (40.1) | 218 (38.7) | 0.63 | | Time intervals (mins), median (IQR) | | | | | | Onset to paramedic evaluation | 16 (8-35) | 15 (8-32) | 17 (8-39) | 0.22 | | Onset to ED arrival | 58 (46-79) | 57 (46-75) | 60 (46-83) | 0.10 | | Severity scores | | | | | | Prehospital GCS, `median (IQR) | 15 (14-15) | 15 (14-15) | 15 (14-15) | 0.08 | | Prehospital LAMS, median (IQR) | 4 (3-5) | 4 (3-5) | 4 (3-5) | 0.53 | | Serum magnesium `level mean (SD) | 2.86 (1.3) | 3.74 (1.2) | 1.97 (0.40) | <0.0001 | | Patients with CAEs, (%) | 159 (14.1) | 79 (14.0) | 80 (14.3) | 0.93 | | Number of CAEs, (%) | | | | | | 0 | 967 (85.9) | 486 (86.0) | 481 (85.7) | 0.29 | | 1 | 136 (12.1) | 64 (11.3) | 72 (12.8) | | 2 | 21 (1.9) | 13 (2.3) | 8 (1.4) | | 3 | 2 (0.2) | 2 (0.4) | 0 (0.0) |
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