Cardiovascular Therapeutics

Research Article

Analysis of Clinical Efficacy of Traditional Chinese Medicine in Recovery Stage of Stroke: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.


	Author, year	Cases T/C	Diagnostic standard	Age (years) range, mean		Sex male/female

TCMs	Wang Yuxiu, 2017	41/41	DCIS	T: 52-73, 59.8	C: 53-73, 59.9	T: 28/13	C: 29/12
	Zhao Xiaoli, 2017	44/43	NE	T: 43-59, 49.77	C: 42-58, 49.71	T: 27/17	C: 27/17
	Chen Si, 2016	29/29	MPDCD	T: 53-78, 61.15	C: 52-77, 62.18	T: 20/9	C: 18/11
	Li Shefang, 2016	40/40	CDECEA	T, 46-73, 65.9	C: 48-76, 66.3	T: 23/17	C: 22/18
	Zhang Kefei, 2018	58/58	MPDCD	T: 40-73, 58.93	C: 41-75, 59.37	T: 35/23	C: 34/24
	Zhao Jing, 2016	75/75	NR	T: 42-75, 60.6	C: 43-76, 58.8	T: 51/24	C: 48/27
	Yang Zhenwei, 2017	33/32	ATCICE	NR	NR	NR	NR
	Liu Yupeng, 2016	50/50	CEDEA & GPTCDCSTCM	T: 58-70, 61.19	C: 58-70, 61.19	T: 27/23	C: 26/24
	Cao Ying, 2014	198/66	ACILIWM & SDSQDBSS	T: 40-70, 63.1	C: 40-70, 63.3	T: 111/87	C: 45/20
	Fu Yaping, 2018	60/60	GDTAISC (2010)	T: 50-78, 62.1	C: 48-76, 60.2	T: 38/22	C: 36/24
	Li Yaorong, 2015	33/33	CDETEA	T: 34-78	C: 33-77	T: 19/14	C: 18/15
	Wu Xiuhua, 2018	65/65	MPDCD	T: 52-75, 62.3	C: 50-73, 61.2	T: 34/31	C: 36/29
	Liu Weicheng, 2017	53/52	NR	T: 35-80, 36.8	C: 36-78, 59.8	T: 29/24	C: 30/22
	Chen Rong, 2011	40/40	CDECEA & MPDCD	T: 55-82, 70.22	C, 52-78, 66.78	T: 28/12	C: 30/10
	Li Naiqian, 2017	40/40	GDTAISC (2010) & GPCRND	T: 46-75, 64.73	C: 48-78, 64.85	T: 23/17	C: 22/18
	Zhong Lingyi, 2019	53/53	GDAISC	T: 47-78, 59.56	C: 45-77, 60.25	T: 30/23	C: 28/25
	Jia Liang, 2017	70/70	MPDCD	T: 53-75, 64.90	C: 50-73, 64.72	T: 45/25	C: 43/27
	Zhang Jin, 2004	76/60	DCWM & DCTCM	T: 40-70, 57.25	C: 42-71, 58.13	T: 49/27	C: 36/24
	Wang Chengtai, 2016	62/63	GDTAISC (2010) & CDECEA	T: 37-80, 61.17	C: 34-81, 62.25	T: 32/30	C: 32/31
	Niu Ben, 2016	48/48	GDTAISC (2010) & DCQBSS	T: 61-73, 64.9	C: 60-72, 65.7	T: 31/17	C: 33/15
	Wang Aili, 2019	47/47	GDTAISC (2014) & CDECEA	T: 44-79, 57.02	C: 43-76, 56.87	T: 25/22	C: 27/20
	Yuan Li, 2005	92/92	DCTCM	T: 40-70, 58.37	C: 42-71, 58.23	T: 54/38	C: 56/36
	Bian Yonghong, 2017	93/93	GPCRND	T: 47-82, 63.1	C: 44-79, 63.8	T: 51/42	C: 49/44
	Lou Fei, 2019	72/72	GCDTCDC (2016) & CPTCM	T: 45-75, 61.26	C: 45-72, 60.85	T: 44/28	C: 40/32

ACU	Cai Jingjing, 2012	60/60	CDECEA & RDCFNCCD	T: 35-75, 64.5	C: 38-73, 64.6	T: 29/31	C: 31/29
	Chen Dan, 2018	30/30	RDCFNCCD	T: 45-80, 64	C: 38-80, 65	T: 19/11	C: 22/8
	Dai Shuqing, 2015	30/26	MPDVKCD (1997) & SSDEA	T: 60-75, 67.1	C: 54-74, 64.9	T: 19/11	C: 16/10
	Deng Xiaodong, 2018	73/73	GSPISTIAC (2014) & CDTEDSTCM	T: 45-75, 62.8	C: 45-78, 63.7	T: 40/33	C: 39/34
	Du Xin, 2018	35/35	NR	T: 41-65, 51.32	C: 39-72, 50.67	T: 18/17	C: 16/19
	Feng Shengwang, 2016	30/30	GDTAISC	T: 48-72, 60	C: 46-71, 58	T: 18/12	C: 19/11
	Fu Qinhui, 2016	56/56	CDECEA	T: 65.68	C: 63.80	T: 36/20	C: 35/21
	Fu Xiaofeng, 2019	34/26	RDCFNCCD & DCAFSATCM	T: 60.35	C: 62.33	T: 18/16	C: 14/12
	Gao Ting, 2018	46/46	GDTAISC	T: 63.76	C: 64.23	T: 25/21	C: 27/19
	Huang Wei, 2018	98/98	GDTAISC	NR	NR	NR	NR
	Jiang Ming, 2018	58/58	RDCFNCCD	T: 58.47	C: 57.02	T: 38/20	C: 39/19
	Lin Biyu, 2018	45/45	NR	T: 47-73, 65.32	C: 46-71, 64.48	T: 32/13	C: 30/15
	Liu Sang, 2018	82/82	MPDVKCD & SSDEA	T: 66.7	C: 67.9	T: 56/26	C: 51/31
	Peng Shaokun, 2015	38/38	SSDEA	T: 43-78, 61.6	C: 41-81, 61.2	T: 22/16	C: 24/14
	Shi Youjia, 2018	66/66	NR	NR	NR	NR	NR
	Shi Yunhua, 2017	40/40	CDECEA	T: 51-78, 68.4	C: 50-78, 68.6	T: 25/15	C: 24/16
	Song Yi, 2017	42/42	SSDEA	T: 60.43	C: 60.29	T: 19/23	C: 24/18
	Tang Youbin, 2014	34/34	SSDEA	T: 31-64, 43	C: 28-66, 38	T: 23/11	C: 28/6
	Wang Jing, 2019	35/35	NR	NR	NR	NR	NR
	Xiao Yu, 2013	68/50	NR	T: 40-71, 51.9	C: 41-72, 52.1	T: 41/27	C: 31/19
	Xie Xiaojuan, 2018	43/40	MPDVKCD	T: 56.94	C: 58.15	T: 22/21	C: 21/19
	Xu Lei, 2017	30/30	CDTEDSTCM	T: 40-74, 58	C: 42-74, 61	T: 15/15	C: 16/14
	Xu Wansong, 2017	42/42	MPDVKCD	T: 44-71, 56.18	C: 45-73, 56.32	T: 28/14	C: 25/17
	Zhang Liao, 2018	50/50	GPTCDC & CDECEA	T: 40-77, 55.9	C: 41-76, 56.4	T: 34/16	C: 33/17
	Zhang Ningxia, 2010	40/40	RDCFNCCD	T: 40-80, 65.9	C: 40-80, 69.2	T: 26/14	C: 24/16
	Zhou Minya, 2016	58/58	MPDVKCD	T: 59.45	C: 58.16	T: 39/19	C: 35/23
	Zhou Shuxin, 2018	60/60	RDCFNCCD	T: 49-84, 69.1	C: 51-85, 70.4	T: 38/22	C: 41/19

OTTCM	Yao Baonong, 2014	30/30	CDECEA (1995)	T: 50-76, 60.9	C: 52-77, 61.7	T: 18/22	C: 16/14
	Zhu Xiaolei, 2017	30/30	GPTCDC (2007)	T: 51-76, 61.5	C: 50-78, 62.3	T: 16/14	C: 17/13
	Yan Jiang, 2017	49/49	NR	T: 55-75, 62.9	C: 55-75, 63.1	T: 32/17	C: 31/18
	Qi Jiangmin, 2017	41/39	MPDAKCD & CDECEA	T: 18-75, 53.6	C: 18-75, 52.8	T: 25/16	C: 17/22
	Huo and Wang, 2014	36/32	CDECEA (1996)	T: 59	C: 62	T: 20/16	C: 18/14
	Guo Chenggang, 2015	36/36	DCCA (1995)	T: 55.7	C: 56.2	T: 20/16	C: 19/17
	Ding Min, 2018	40/39	CDECEA (1996) & MPDAKCD	T: 46-69, 61.0	C: 44-70, 60.2	T: 19/21	C: 20/19
	Yan Hongda, 2018	45/45	NR	T: 65.65	C: 63.21	T: 25/20	C: 28/17
	Zhao Lijuan, 2013	40/40	NR	T: 44-78, 62.72	C: 48-80, 62.56	T: 22/18	C: 19/21
	Nie Bin, 2013	40/40	CETEDA & MPDAKCD	T: 38-75, 58	C: 38-75, 59	T: 23/17	C: 21/19
	Hou and Liu, 2014	36/32	CDECEA (1996)	T: 59.2	C: 61.8	T: 20/16	C: 18/14
	Huo Xinhui, 2016	36/32	MPDAKCD & CDECEA	T: 52.25	C: 54.88	T: 25/11	C: 19/13
	Yang Haixia, 2016	30/30	ESCETCMDA (1995) & GDTALSC (2010)	T: 28-67	C: 31-70	T: 20/10	C: 18/12
	Li Chaoming, 2018	43/43	CDTEDSTCM & DCA	T: 48-76, 62.4	C: 46-77, 63.1	T: 25/18	C: 24/19
	Zhao Yang, 2017	39/39	NR	T: 48-74, 62.04	C: 47-73, 61.75	T: 22/17	C: 21/18
	Wang Ling, 2014	30/30	SDTRMC	T: 53.53	C: 51.53	T: 21/9	C: 18/12

ATCICE: atherosclerotic thrombotic cerebral infarction or cerebral embolism; ACU: acupuncture; ACILIWM: arteriosclerosis cerebral infarction or lacunar infarction in western medicine; C: control group; CEDEA: criteria for evaluation of diagnostic efficacy of apoplexy; CDECEA: criteria for diagnosis and evaluation of curative effect of apoplexy; CDTEDSTCM: criteria for diagnosis and therapeutic effect of diseases and syndromes of traditional Chinese medicine; CETEDA: criteria for evaluation of therapeutic effect in the diagnosis of apoplexy; CPTCM: clinical pathway of traditional Chinese medicine in 22 specialties and 95 diseases; CDETEA: criteria for diagnosis and evaluation of therapeutic effect of apoplexy in traditional Chinese medicine; DCAFSATCM: diagnostic criteria for apoplexy formulated by the state administration of traditional Chinese medicine; DCA: diagnostic criteria for apoplexy; DCCA: diagnostic criteria of cerebral apoplexy; DCIS: diagnostic criteria of ischemic stroke; DCQBSS: diagnostic criteria of qi deficiency and blood stasis syndrome in traditional Chinese medicine; DCTCM: diagnostic criteria of traditional Chinese medicine; DCWM: diagnostic criteria of western medicine; ESCETCMDA: evaluation standard of curative effect of traditional Chinese medicine diagnosis of apoplexy; GSPISTIAC: guidelines for secondary prevention of ischemic stroke and transient ischemic attack in China; GCDTCDC: guidelines and consensus for diagnosis and treatment of cerebrovascular diseases in China; GPTCDC: guidelines for the prevention and treatment of cerebrovascular diseases in China; GDAISC: guidelines for the diagnosis of acute ischemic stroke in China; GDTAISC: guidelines for the diagnosis and treatment of acute ischemic stroke in China; GDTALSC: guidelines for the diagnosis and treatment of acute ischemic stroke in China 2010; GPCRND: guiding principles for clinical research of new drugs of traditional Chinese medicine; GPTCDCSTCM: guidelines for the prevention and treatment of cerebrovascular diseases of the Chinese society of traditional Chinese medicine; MPDVKCD: main points of diagnosis of various kinds of cerebrovascular diseases; MPDCD: main points of diagnosis of all kinds of cerebrovascular diseases; MPDAKCD: main points of diagnosis of all kinds of cerebrovascular diseases; NR: no report; NE: neurology; OTTCM: other treatments of traditional Chinese medicine; RDCFNCCD: reference to the diagnostic criteria of the fourth National Conference on Cerebrovascular Diseases; SDSQDBSS: syndrome differentiation standard of qi deficiency and blood stasis syndrome in traditional Chinese medicine; SDTRMC: standard for diagnosis and treatment of rehabilitation medicine in China; SSDEA: scoring standard for diagnostic efficacy of apoplexy; T: trial group; TCMs: traditional Chinese medicines.