Research Article
Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients
Table 1
Top 10 up- and downregulated DEGs in GSE29111.
| | Gene symbol | value | LogFC | Gene function | PubMed IDs |
| | Upregulated | | TSTA3 | 1.29-05 | 1.0854319 | GDP-4-dehydro-D-rhamnose reductase activity | 11698403 | | SLC22A11 | 2.64-05 | 1.7937471 | Organic anion transmembrane transporter activity | 15102942 | | ALDH5A1 | 3.94-05 | 1.1577679 | Protein homodimerization activity | 16199352 | | PLA2G16 | 5.57-05 | 1.2325045 | Catalyzes the release of fatty acids from phospholipids in adipose tissue | 17374643 | | DTNA | 7.35-05 | 2.0915867 | Clustering of nicotinic acetylcholine receptors | 11353857 | | HIF3A | 7.63-05 | 1.4873978 | Adaptive response to hypoxia | 11573933 | | POLL | 1.25-04 | 1.3674519 | Repair polymerase | 10982892 | | CTDSPL | 1.42-04 | 2.1596408 | Negatively regulates RNA polymerase II transcription | 20379614 | | ENDOV | 1.43-04 | 1.6507937 | Cleaves inosine-containing RNAs | 23912683 | | THSD4 | 1.49-04 | 2.1230904 | Promotes FBN1 matrix assembly | 19734141 | | Downregulated | | KYAT1 | 8.00-06 | -2.1991848 | CCBL activity and transaminase activity with many amino acids | 19826765 | | LOC101927044 | 1.48-05 | -1.4311556 | Uncharacterized | — | | ADAMTS9 | 1.58-05 | -1.5421577 | Metallopeptidase activity | 12514189 | | ETS1 | 2.41-05 | -1.1693245 | Transcription factor binding | 10698492 | | PNMA3 | 2.82-05 | -1.4922227 | Nucleic acid binding | 16344560 | | MARC2 | 4.20-05 | -2.2687039 | Nitrate reductase activity | 20808825 | | HSD17B12 | 4.54-05 | -2.1426028 | Long fatty acid elongation | 20937905 | | SCRT1 | 4.62-05 | -1.489692 | Transcriptional repressor | 11274425 | | PNMA6A | 6.01-05 | -1.3616952 | Functional ribosomal frameshift signal | 16407312 | | APOC1 | 8.06-05 | -1.16521 | Fatty acid binding | 17339654 |
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