Research Article

Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients

Table 3

Hub genes in GSE29111 regulated by hsa-miR-127-5p in GSE53211.

ID valueLogFCGene symbolGene titleGene function

210727_at0.01372.5508641-2.99651-1.0294165CALCACalcitonin-related polypeptide alphaDilates vessels including the coronary, cerebral, and systemic
235287_at0.001773.297353-1.26724-1.1501461CDK6Cyclin-dependent kinase 6Cell cycle and differentiation; delays senescence
205386_s_at0.012.6727568-2.73565-1.042301MDM2MDM2 protooncogeneMediates ubiquitination and subsequent proteasome degradation of DYRK2 in nucleus
1558708_at0.00553-2.8958494-2.235421.6471658NRXN1Neurexin 1Synaptic signal transmission
206359_at0.0283-2.2568286-3.586931.1075956SOCS3Suppressor of cytokine signaling 3Inhibits cytokine signal transduction by binding to tyrosine kinase receptors
211527_x_at0.0264-2.2854412-3.531991.1348245VEGFAVascular endothelial growth factor AInduces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels
1565702_at0.02952.2381206-3.62256-1.3151998SMAD4SMAD family member 4TGF-mediated signaling
214952_at0.03982.1090612-3.86171-1.1379034NCAM1Neural cell adhesion molecule 1Cell adhesion molecule