Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coronary Intervention
Table 1
In-hospital demographic, clinical, and laboratory characteristics of patients.
Parameters
All patients (: 537)
Low () (: 268)
High () (: 269)
value
Demographic parameters
Age (year)
0.005
Male (, %)
422(78.6)
206(76.9)
216(80.3)
0.332
Clinical history
HT (, %)
329(61.3)
136(58)
193(71.7)
0.039
DM (, %)
255(47.5)
129(48.1)
126(46.8)
0.764
HL (, %)
326(60.7)
164(61.2)
162(60.2)
0.818
CAD (, %)
122(22.7)
63(23.5)
59(21.9)
0.663
Smoking (, %)
217(40.4)
95(35.4)
122(45.4)
0.019
Clinical parameters
Anterior MI (, %)
256(47.7)
125(46.6)
131(48.7)
0.633
Inferior MI (, %)
256(47.7)
128(47.8)
128(47.6)
0.967
Other localization MI (, %)
25(4.7)
15(5.6)
10(3.7)
0.301
SBP (mmHg)
<0.001
DBP (mmHg)
0.329
Heart rate/min
0.017
HF (, %)
102(19)
39(14.6)
63(23.4)
0.009
LVEF (%)
55(45-60)
60(48.5-63)
54(45-60)
<0.001
Inotropic treatment (, %)
104(19.4)
37(13.8)
67(24.9)
0.001
IV diuretic treatment (, %)
79(14.7)
31(11.6)
48(17.8)
0.040
Gp2b3a treatment (, %)
86(16)
33(12.3)
53(19.7)
0.020
IABP (, %)
23(4.3)
6(2.2)
17(6.3)
0.020
GRACE score
107(87-129)
106(87-126.5)
109(87-131)
0.484
Length of hospitalization (days)
5(4-5)
5(4-5)
5(4-5)
0.353
Laboratory parameters
ABG level (mg/dl)
140(115-197)
138(112.5-198)
145(118-197)
0.299
FBG level (mg/dl)
108(92-151)
108(90-154)
109(92-148)
0.516
HbA1c
6.1(5.6-7.2)
6.1(5.6-7.3)
6(5.6-7.2)
0.701
A-Cre level (mg/dl)
0.89(0.76-1.03)
0.86(0.74-1)
0.9(0.8-1.09)
0.003
PP-Cre level (mg/dl)
0.91(0.8-1.1)
0.9(0.79-1.09)
0.93(0.8-1.2)
0.030
CreCl (ml/min)
87.26(69.28-99.01)
86.99(71.18-99)
88(68-99.4)
0.529
Peak trop-T (ng/ml)
50000(15.91-50000)
40.98(8.9-50000)
50000(24.65-50000)
<0.001
Peak trop-T(ng/ml) > 50000 (, %)
282(52.5)
115(42.9)
167(62.1)
<0.001
CRP (mg/dl)
1.78(0.6-6.38)
1.38(0.48-4.07)
2.12(0.73-10.13)
<0.001
Hb (g/dl)
0.090
WBC (×103μ/l)
10.91(8.63-13.5)
8.66(7.37-9.93)
13.3(11.49-15.3)
<0.001
Neutrophil (×103μ/l)
7.16(5-9.8)
5.32(4.13-7.05)
9.57(7.28-11.78)
<0.001
PLT (×103μ/l)
254(208-305)
228(191.5-275.5)
275(232-322)
<0.001
MPV (fl)
8.4(7.6-9.4)
8.8(8.1-9.9)
8(7.2-8.8)
<0.001
Lymphocyte (×103)
2.31(1.55-3.3)
2.2(1.54-2.96)
2.49(1.56-4.07)
0.001
WMR
1286(989-1645)
989(844-1142)
1645(1450-1948)
<0.001
ABG: admission blood glucose; A-CRE: admission creatinine; CAD: coronary artery disease; CreCl: creatinine clearance; CRP: C-reactive protein; DBP: diastolic blood pressure; DM: diabetes mellitus; FBG: fasting blood glucose; Gp2b3a: glycoprotein 2b3a antagonist; Hb: hemoglobin; HbA1C: hemoglobin A1C; HF: heart failure; HL: hyperlipidemia; HT: hypertension; IABP: intraaortic balloon pump; IV: intravenous; LVEF: left ventricular ejection fraction; MI: myocardial infarction; MPV: mean platelet volume; PLT: platelet; PP-Cre: postprocedural creatinine; SBP: systolic blood pressure; trop: troponin; WBC: white blood cell; WMR: white blood cell count to mean platelet volume. Data are presented as , median (0.25–0.75 percentiles), and (%). Student’s -test, Mann-Whitney test, and Pearson chi-square test were used. Bold data are with statistical significance.
