Research Article

The Effect of 3-Month Growth Hormone Administration and 12-Month Follow-Up Duration among Heart Failure Patients Four Weeks after Myocardial Infarction: A Randomized Double-Blinded Clinical Trial

Table 1

Characteristics of study participants across different categories of intervention or control group at baseline and 12 months after study initiation.

GH group ()Placebo group () value

BaselineAge (years)0.21
BMI (kg/m2)0.64
Education level (≥diploma)87.51000.93
Occupation statusEmployee62.5500.48
Retired37.550
Blood pressure (mmHg)Systolic0.09
Diastolic
Hemoglobin (g/dl)0.51
Cholesterol (mg/dl)0.32
Triglyceride (mg/dl)0.59
LDL-C (mg/dl)0.66
HDL-C (mg/dl)0.18
eGFR (ml/min/1.73m2)0.88
Medication usage (%)ACEI/ARB1001000.18
β-Blocker100100
COX-inhibitors100100
HMG COA reductase inhibitor100100
Thienopyridines100100

After 12 monthsAge (years)0.13
Weight (kg)0.38
BMI (kg/m2)0.28
Blood pressure (mmHg)Systolic0.75
Diastolic0.65
Hemoglobin (g/dl)0.85
Cholesterol (mg/dl)0.66
Triglyceride (mg/dl)0.75
LDL-C (mg/dl)0.38
HDL-C (mg/dl)0.59
eGFR (ml/min/1.73m2)0.56
Medication usage (%)ACEI/ARB1001001.00
β-Blocker100100
COX-inhibitors100100
HMG COA reductase inhibitor100100
Thienopyridines100100

GH: growth hormone; BMI: body mass index; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; eGFR: estimated glomerular filtration rate; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; COX-inhibitor: cyclooxygenase inhibitor; HMG-CoA: 3-hydroxy-3-methyl-glutaryl-CoA.