Molecular Signatures of Human Chronic Atrial Fibrillation in Primary Mitral Regurgitation

Figure 3

Hierarchical cluster analysis of gene expression microarrays of right and left atrial biopsies from AFib patients with primary mitral regurgitation compared to controls (S.R.). Heatmap shows the clusters how 178 differentially expressed genes separate all samples using 1.5-fold change as the threshold. Consequential 178 differentially expressed genes outcome from comparing gene expression profiles between AFib vs. S.R. of all atria tissues and separate AFib samples from S.R. samples with 85% success. Columns represent samples, and rows represent differentially expressed genes. As can be seen on the color bar, red indicates increased gene expression, and green indicates decreased gene expression. Heat and intensity of red or green color appear according to the fold-change.