Patients with Coronary Artery Disease Have Lower Levels of Antibody to Heat-Stressed Fibroblast Derived Proteins, versus Normal Subjects

Figure 4

The serum levels of anti-HSP antibody in CAD patients and normal control which shows a diagnostic value of this type of antibody. (a) The anti-HSP IgG was measured by ELISA in serum of CAD patients () as well as in normal control (). Results are expressed in arbitrary units per milliliter (AU/mL), and the horizontal lines indicated the median. value was equal to 0.0006 when two groups compared with the Mann–Whitney test. (b) The receiver operating characteristic (ROC) curve analysis showed 64% sensitivity and 74% specificity for a cut-off value of 30.5 (AU/mL). The area under the curve (AUC) was 0.74 ().

(a)

(b)